Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 3/20 | 0.46 |
| ▸ | HTR2C | P28335 | 3/20 | 0.46 |
| ▸ | HTR2B | P41595 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ACE | P12821 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10855534 | 1.00 | CAPN1 (0.56) | CAPN1SMN1; SMN2HTR2AHTR2CHTR2B | |
| SCHEMBL8498408 | 1.00 | CAPN1 (0.56) | CAPN1SMN1; SMN2HTR2AHTR2CHTR2B | |
| SCHEMBL8498091 | 0.83 | CAPN1 (0.53) | CAPN1HTR2AHTR2CHTR2BKDM4E | |
| SCHEMBL10851353 | 0.83 | CAPN1 (0.53) | CAPN1HTR2AHTR2CHTR2BKDM4E | |
| SCHEMBL3804693 | 0.81 | SMN1; SMN2 (0.47) | CAPN1SMN1; SMN2KDM4EALOX15TSHR | |
| SCHEMBL5847071 | 0.78 | ACE (0.54) | ACE | |
| SCHEMBL4278365 | 0.78 | ACE (0.54) | ACE | |
| SCHEMBL28922579 | 0.78 | HTR2C (0.49) | CAPN1SMN1; SMN2HTR2AHTR2CHTR2B | |
| SCHEMBL5847068 | 0.78 | ACE (0.54) | ACE | |
| SCHEMBL9601440 | 0.78 | CAPN1 (0.43) | CAPN1KDM4EALOX15TSHRSIRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4563306-A | CONSCIOUSNESS DISORDERS | TANABE SEIYAKU CO., LTD. (JP) | 1986-01-07 | — | — | US | disclosed |
| EP-0134582-A2 | Novel peptides and process for preparing the same and pharmaceutical composition | Tanabe Seiyaku Co., Ltd. (JP) | 1985-03-20 | — | — | EP | disclosed |