Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH2 | P25021 | 14/20 | 0.53 |
| ▸ | HRH1 | P35367 | 14/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11182660 | 0.95 | HRH2 (0.52) | HRH2HRH1ALDH1A1KDM4EPOLB | |
| SCHEMBL4050766 | 0.89 | ALDH1A1 (0.53) | HRH2HRH1ALDH1A1KDM4EPOLB | |
| SCHEMBL29991910 | 0.87 | HRH2 (0.56) | HRH2HRH1POLBSMN1; SMN2HRH3 | |
| SCHEMBL14670199 | 0.86 | HRH2 (0.56) | HRH2HRH1ALDH1A1POLBHTT | |
| SCHEMBL27629332 | 0.84 | HRH2 (0.59) | HRH2HRH1ALDH1A1POLBHTT | |
| SCHEMBL11392680 | 0.84 | HRH2 (0.55) | HRH2HRH1ALDH1A1POLBHTT | |
| SCHEMBL11747160 | 0.83 | HRH2 (0.60) | HRH2HRH1ALDH1A1POLBHTT | |
| SCHEMBL3270714 | 0.83 | ALDH1A1 (0.59) | HRH2HRH1ALDH1A1POLBHTT | |
| SCHEMBL5537946 | 0.83 | HRH2 (0.53) | HRH2HRH1ALDH1A1POLBHTT | |
| SCHEMBL9047895 | 0.83 | HRH2 (0.60) | HRH2HRH1ALDH1A1POLBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0095029-B1 | 5-THIO-TETRAZOL COMPOUNDS AND THEIR PREPARATION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-11-05 | — | — | EP | disclosed |
| US-4563524-A | INTERMEDIATES FOR CEPHALOSPORIN ANTIBIOTICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-01-07 | — | — | US | disclosed |
| EP-0029998-B1 | CEPHEM COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1985-03-06 | — | — | EP | disclosed |
| US-4443443-A | BACTERICIDES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-04-17 | — | — | US | disclosed |
| EP-0095029-A1 | 5-Thio-tetrazol compounds and their preparation | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-11-30 | — | — | EP | disclosed |
| EP-0029998-A2 | Cephem compounds, processes for their preparation and pharmaceutical compositions containing them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-06-10 | — | — | EP | disclosed |