Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | GBA1 | P04062 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10857201 | 1.00 | HTT (0.41) | HTTATMRAB9ASMN1; SMN2MEN1 | |
| SCHEMBL10858908 | 0.96 | LMNA (0.41) | HTTATMRAB9ASMN1; SMN2MEN1 | |
| SCHEMBL10854542 | 0.96 | LMNA (0.41) | HTTATMRAB9ASMN1; SMN2MEN1 | |
| SCHEMBL10854141 | 0.86 | MEN1 (0.46) | RAB9ASMN1; SMN2MEN1LMNAKMT2A | |
| SCHEMBL10856579 | 0.86 | MEN1 (0.46) | RAB9ASMN1; SMN2MEN1LMNAKMT2A | |
| SCHEMBL10853382 | 0.85 | MEN1 (0.47) | RAB9ASMN1; SMN2MEN1LMNAKMT2A | |
| SCHEMBL10856216 | 0.82 | EPHX1 (0.50) | SMN1; SMN2MEN1LMNAKMT2AHPGD | |
| SCHEMBL10853307 | 0.81 | MEN1 (0.35) | HTTATMRAB9ASMN1; SMN2MEN1 | |
| SCHEMBL10854088 | 0.81 | RAB9A (0.38) | HTTATMRAB9ASMN1; SMN2MEN1 | |
| SCHEMBL10856673 | 0.80 | HPGD (0.54) | HTTHPGDHSD17B10ALDH1A1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4581372-A | ANTIBODY STIMULANTS;IMMUNOLOGY | TAIHO PHARMACEUTICAL COMPANY LIMITED (JP) | 1986-04-08 | — | — | US | disclosed |
| US-4340543-A | ANTICANCER AGENTS, ANTITUMOR AGENTS, IMMUNOSTIMULANTS | TAIHO PHARMACEUTICAL COMPANY LIMITED (JP) | 1982-07-20 | — | — | US | disclosed |