SCHEMBL108548

SCHEMBL108548

O=C1OC(=O)c2c(C#Cc3ccccc3)cccc21

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
ALDH1A1 P00352 3/20 0.43
MAPT P10636 3/20 0.43
NPC1 O15118 2/20 0.43
KDM4E B2RXH2 2/20 0.43
MEN1 O00255 2/20 0.43
CYP1A2 P05177 2/20 0.43
CYP3A4 P08684 2/20 0.43
CYP2C9 P11712 2/20 0.43
HPGD P15428 2/20 0.43
CYP2C19 P33261 2/20 0.43
KMT2A Q03164 2/20 0.43
HSD17B10 Q99714 2/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
APP P05067 1/20 0.41
CA12 O43570 2/20 0.41
CA2 P00918 2/20 0.41
CA9 Q16790 2/20 0.41
RAB9A P51151 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29546502 1.00 ALOX15 (0.43) ALOX15TDP1ALDH1A1MAPTNPC1
SCHEMBL12814518 0.89 TDP1 (0.48) ALOX15TDP1ALDH1A1MAPTKDM4E
SCHEMBL28740199 0.85 CA12 (0.44) ALOX15TDP1ALDH1A1KDM4EMEN1
SCHEMBL2812660 0.82 GRM5 (0.41) CYP1A2CYP3A4CYP2C9CYP2C19GRM5
SCHEMBL2810822 0.82 TYMS (0.39) ALOX15TDP1CYP1A2CA2TYMS
SCHEMBL3447273 0.81 TYMS (0.38) ALOX15TDP1CYP1A2CA2TYMS
SCHEMBL2810821 0.80 TYMS (0.43) ALOX15TDP1ALDH1A1MAPTKDM4E
SCHEMBL2710468 0.79 ALOX15 (0.41) ALOX15TDP1ALDH1A1MAPTRAB9A
SCHEMBL13741752 0.78 GRM5 (0.49) ALOX15TDP1ALDH1A1MAPTNPC1
SCHEMBL24305985 0.76 GRM5 (0.36) ALOX15TDP1ALDH1A1MAPTNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 293 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122080406-A High-temperature-resistant and thermally-dimensionally-stable soluble polyimide resin and preparation method and application thereof 2026-05-26 CN claimed
CN-119978801-A Polyimide resin composition, preparation method thereof and polyimide resin adhesive film 中国科学院化学研究所 2025-05-13 CN claimed
CN-119636123-A Preparation method of polyimide resin composite material 中国航空制造技术研究院 2025-03-18 CN claimed
CN-119041193-A Preparation method of surface modified polyimide fiber 北京化工大学 2024-11-29 CN claimed
CN-118812881-A Interpenetrating network type polyimide molding powder, preparation method and product 陕西普利美材料科技有限公司 2024-10-22 CN claimed
CN-114369243-B Application of thermosetting polyimide in preparing high-temperature-resistant resin matrix composite material 中国科学院宁波材料技术与工程研究所 2024-09-13 CN claimed
CN-118325082-B Polyimide and preparation method and application thereof 湖南恒缘新材科技股份有限公司 2024-08-27 CN claimed
CN-118325082-A Polyimide and preparation method and application thereof 湖南恒缘新材科技股份有限公司 2024-07-12 CN claimed
CN-118221935-A Polyamide acid slurry with low water absorption rate and polyimide film prepared from polyamide acid slurry 武汉柔显科技股份有限公司 2024-06-21 CN claimed
CN-117656565-A High-temperature-resistant continuous fiber honeycomb core cell shaping method 中航复合材料有限责任公司 2024-03-08 CN claimed
JP-2002511902-A 2002-04-16 JP claimed
US-6222007-B1 TACK; QUALITY THE UNITED STATES OF AMERICA AS REPRESENTED BY THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION 2001-04-24 US claimed
EP-1000108-A4 AQUEOUS POLYIMIDE PROCESS COMMW SCIENT IND RES ORG (AU) 2000-10-11 EP claimed
US-6084106-A Adhesion promoters and methods of their synthesis and use THIOKOL CORPORATION (US) 2000-07-04 US claimed
EP-1000108-A1 AQUEOUS POLYIMIDE PROCESS COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2000-05-17 EP claimed
WO-1999062989-A1 FILMS, PREIMPREGNATED TAPES AND COMPOSITES MADE FROM POLYIMIDE 'SALT-LIKE' SOLUTIONS THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (NASA) (US) 1999-12-09 WO claimed
WO-1999006470-A1 AQUEOUS POLYIMIDE PROCESS COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 1999-02-11 WO claimed
US-5681967-A ENDCAPPING POLYAMIC ACIDS THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) 1997-10-28 US claimed
US-5567800-A MOLECULAR WEIGHT CONTROLLED AROMATIC POLYIMIDES; ELONGATION, HIGH GLASS TRANSITION TEMPERATURE, TOUGHNESS THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) 1996-10-22 US claimed
US-5478913-A Copolymerizing biphenyl dianhydride as ester/acid/ with mix of m- or p-phenylenediamines and aminophenoxybenzene component encapped with phthalic anhydride or ethynyl-group amine or anhydride; heat, oxidation resistant; prepregs E. I. DU PONT DE NEMOURS AND COMPANY (US) 1995-12-26 US claimed