Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 4/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 6/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.40 |
| ▸ | CYP2B6 | P20813 | 3/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.40 |
| ▸ | CYP2E1 | P05181 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL108548 | 0.82 | ALOX15 (0.43) | GRM5CYP2C9CYP2C19CYP2D6CYP3A4 | |
| SCHEMBL29546502 | 0.82 | ALOX15 (0.43) | GRM5CYP2C9CYP2C19CYP2D6CYP3A4 | |
| SCHEMBL12814518 | 0.81 | TDP1 (0.48) | — | |
| SCHEMBL28740199 | 0.75 | CA12 (0.44) | GRM5CYP2C9CYP2C19CYP3A4CYP1A2 | |
| SCHEMBL2812659 | 0.72 | GRM5 (0.43) | GRM5CYP1A2 | |
| SCHEMBL2810259 | 0.72 | CREBBP (0.39) | CYP2C9CYP2C19CYP2D6CYP3A4CYP1A2 | |
| SCHEMBL2815384 | 0.72 | ALDH1A1 (0.46) | GRM5CYP1A2 | |
| SCHEMBL3796332 | 0.72 | CYP2A6 (0.67) | GRM5CYP2A6CYP2C9CYP2B6CYP2C19 | |
| SCHEMBL2710468 | 0.72 | ALOX15 (0.41) | — | |
| SCHEMBL2810822 | 0.71 | TYMS (0.39) | GRM5CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100240908-A1 | ACETYLENE COMPOUND | FUJIFILM CORPORATION (JP) | 2010-09-23 | — | — | US | disclosed |
| EP-2202221-A1 | ACETYLENE COMPOUND | Fujifilm Corporation (JP) | 2010-06-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100240908-A1 | ACETYLENE COMPOUND | NAT1, KATNA1, KAT2B | GRM5 2797/4885CYP2A6 2596/4885CYP2C9 1564/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.