Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL209024 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL10852462 | 0.94 | — | — | |
| SCHEMBL22449405 | 0.80 | — | — | |
| Urea SCHEMBL11495730 | 0.74 | ALDH1A1 (0.47) | — | |
| SCHEMBL971189 | 0.71 | — | — | |
| SCHEMBL13089248 | 0.71 | ALDH1A1 (0.45) | — | |
| Bromide SCHEMBL10828447 | 0.70 | — | — | |
| Methyl Carbamate SCHEMBL29040580 | 0.70 | — | — | |
| Bromide SCHEMBL27962445 | 0.70 | — | — | |
| SCHEMBL6950834 | 0.69 | ALDH1A1 (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4567275-A | 2-(5-AMINO-1,2,4-THIADIAZOL-3-YL)GLYOXYLIC ACID | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-01-28 | — | — | US | disclosed |
| EP-0064582-B1 | STARTING COMPOUNDS FOR PREPARING CEPHEM COMPOUNDS AND PROCESSES FOR THEIR PREPARATION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1985-12-11 | — | — | EP | disclosed |
| EP-0013762-B1 | CEPHEM AND CEPHAM COMPOUNDS, PROCESSES FOR THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1985-03-13 | — | — | EP | disclosed |
| US-4468515-A | CEPRALOSPORINS, MICROBIOCIDES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-08-28 | — | — | US | disclosed |
| US-4425340-A | ANTIBIOTICS, BACTERICIDES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-01-10 | — | — | US | disclosed |
| US-4390534-A | ANTIBIOTICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-06-28 | — | — | US | disclosed |
| US-4381299-A | 7-Amino-thiadiazole oxyimino derivatives of cephem and cepham compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-04-26 | — | — | US | disclosed |
| EP-0064582-A1 | Starting compounds for preparing cephem compounds and processes for their preparation | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1982-11-17 | — | — | EP | disclosed |
| US-4332798-A | ANTIBIOTICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1982-06-01 | — | — | US | disclosed |
| US-4331665-A | ANTIBIOTICS, BACTERICIDES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1982-05-25 | — | — | US | disclosed |
| EP-0013762-A2 | Cephem and cepham compounds, processes for their preparation, pharmaceutical compositions containing them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1980-08-06 | — | — | EP | disclosed |