Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 6/20 | 0.58 |
| ▸ | LMNA | P02545 | 4/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.48 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10650780 | 0.90 | ADORA2B (0.56) | ADORA2BLMNASMN1; SMN2RXFP1MAPK1 | |
| SCHEMBL10649477 | 0.89 | ADORA2B (0.58) | ADORA2BLMNASMN1; SMN2RXFP1MAPK1 | |
| SCHEMBL10653643 | 0.88 | RXFP1 (0.57) | ADORA2BLMNASMN1; SMN2RXFP1MAPK1 | |
| SCHEMBL10652471 | 0.88 | ADORA2B (0.50) | ADORA2BLMNASMN1; SMN2RXFP1MAPK1 | |
| SCHEMBL10649692 | 0.88 | ADORA2B (0.50) | ADORA2BLMNASMN1; SMN2RXFP1MAPK1 | |
| SCHEMBL10649906 | 0.88 | ADORA2B (0.59) | ADORA2BLMNASMN1; SMN2RXFP1MAPK1 | |
| SCHEMBL10649699 | 0.87 | ADORA2B (0.54) | ADORA2BLMNASMN1; SMN2RXFP1MAPK1 | |
| SCHEMBL10649550 | 0.87 | ADORA2B (0.49) | ADORA2BLMNASMN1; SMN2RXFP1MAPK1 | |
| SCHEMBL10653621 | 0.86 | ADORA2B (0.57) | ADORA2BLMNASMN1; SMN2RXFP1MAPK1 | |
| SCHEMBL10651963 | 0.86 | ADORA2B (0.57) | ADORA2BLMNASMN1; SMN2RXFP1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4565817-A | ANTITUSSIVE AGENTS | CHINOIN GYOGYSZER-ES VEGYESZETI TERMEKEK GYARA R.T. (HU) | 1986-01-21 | — | — | US | disclosed |