Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 8/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.53 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | UBE2N | P61088 | 2/20 | 0.51 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10650780 | 0.92 | ADORA2B (0.56) | ADORA2BMAPTSMN1; SMN2RXFP1LMNA | |
| SCHEMBL10649477 | 0.91 | ADORA2B (0.58) | ADORA2BMAPTSMN1; SMN2RXFP1LMNA | |
| SCHEMBL10651743 | 0.91 | ADORA2B (0.61) | ADORA2BMAPTSMN1; SMN2RXFP1LMNA | |
| SCHEMBL10649906 | 0.90 | ADORA2B (0.59) | ADORA2BMAPTSMN1; SMN2RXFP1LMNA | |
| SCHEMBL10649699 | 0.89 | ADORA2B (0.54) | ADORA2BMAPTSMN1; SMN2RXFP1LMNA | |
| SCHEMBL10653621 | 0.88 | ADORA2B (0.57) | ADORA2BMAPTSMN1; SMN2RXFP1LMNA | |
| Hydrochloric Acid SCHEMBL10654590 | 0.87 | ADORA2B (0.56) | ADORA2BMAPTSMN1; SMN2RXFP1LMNA | |
| SCHEMBL10855700 | 0.86 | ADORA2B (0.58) | ADORA2BMAPTSMN1; SMN2RXFP1LMNA | |
| SCHEMBL10650206 | 0.86 | ADORA2B (0.51) | ADORA2BMAPTSMN1; SMN2RXFP1LMNA | |
| SCHEMBL10651589 | 0.86 | LMNA (0.52) | ADORA2BMAPTSMN1; SMN2RXFP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0089028-B1 | THEOPHYLLIN DERIVATIVES, AND PROCESS FOR THEIR PREPARATION | CHINOIN Gyogyszer és Vegyészeti Termékek Gyára RT. (HU) | 1988-05-25 | — | — | EP | claimed |
| EP-0089028-A1 | Theophyllin derivatives, and process for their preparation | CHINOIN Gyogyszer és Vegyészeti Termékek Gyára RT. (HU) | 1983-09-21 | — | — | EP | claimed |
| EP-0089028-B1 | THEOPHYLLIN DERIVATIVES, AND PROCESS FOR THEIR PREPARATION | CHINOIN Gyogyszer és Vegyészeti Termékek Gyára RT. (HU) | 1988-05-25 | — | — | EP | disclosed |
| US-4565817-A | ANTITUSSIVE AGENTS | CHINOIN GYOGYSZER-ES VEGYESZETI TERMEKEK GYARA R.T. (HU) | 1986-01-21 | — | — | US | disclosed |
| EP-0089028-A1 | Theophyllin derivatives, and process for their preparation | CHINOIN Gyogyszer és Vegyészeti Termékek Gyára RT. (HU) | 1983-09-21 | — | — | EP | disclosed |