Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 4/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL472095 | 0.85 | ALDH1A1 (0.43) | OPRM1OPRD1OPRK1ALDH1A1 | |
| SCHEMBL27279165 | 0.83 | PLA2G1B (0.40) | OPRM1 | |
| SCHEMBL27280786 | 0.83 | PLA2G1B (0.40) | OPRM1 | |
| SCHEMBL27282918 | 0.83 | PLA2G1B (0.40) | OPRM1 | |
| Fluoride SCHEMBL23302253 | 0.82 | ALDH1A1 (0.42) | OPRM1OPRD1OPRK1ALDH1A1 | |
| Bromide SCHEMBL7202386 | 0.82 | ALDH1A1 (0.42) | OPRM1OPRD1OPRK1ALDH1A1 | |
| SCHEMBL1582285 | 0.80 | CYP1A2 (0.40) | — | |
| SCHEMBL11501745 | 0.80 | ALDH1A1 (0.37) | OPRM1OPRD1OPRK1ALDH1A1 | |
| SCHEMBL4401510 | 0.76 | ALDH1A1 (0.34) | ALDH1A1 | |
| SCHEMBL20438511 | 0.74 | LMNA (0.41) | OPRM1OPRD1OPRK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4593100-A | 3A,4,7,7a-tetrahydro-3,6,7a-trimethyl-4-substituted phenyl-isoxazolo[5,4-b]pyridine-5-carboxylic acid esters | AMERICAN HOME PRODUCTS CORPORATION (US) | 1986-06-03 | — | — | US | disclosed |