Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.66 |
| ▸ | SIRT3 | Q9NTG7 | 5/20 | 0.60 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.59 |
| ▸ | EYA3 | Q99504 | 2/20 | 0.59 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.57 |
| ▸ | KDM5A | P29375 | 3/20 | 0.56 |
| ▸ | KDM7A | Q6ZMT4 | 3/20 | 0.56 |
| ▸ | KDM4A | O75164 | 1/20 | 0.55 |
| ▸ | ING2 | Q9H160 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | THRA | P10827 | 2/20 | 0.55 |
| ▸ | THRB | P10828 | 2/20 | 0.55 |
| ▸ | MLNR | O43193 | 1/20 | 0.55 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.55 |
| ▸ | PHF2 | O75151 | 1/20 | 0.55 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10679251 | 0.89 | SMPD1 (0.66) | SIRT3EYA3SMPD1KDM5AKDM7A | |
| SCHEMBL10856948 | 0.89 | SIRT3 (0.59) | TTRSIRT3PTPN1EYA3SMPD1 | |
| SCHEMBL10854519 | 0.85 | SIRT3 (0.59) | TTRSIRT3PTPN1EYA3SMPD1 | |
| SCHEMBL11847926 | 0.85 | TTR (0.62) | TTRSIRT3PTPN1EYA3KDM5A | |
| SCHEMBL10672374 | 0.85 | KDM5A (0.76) | TTRSIRT3PTPN1EYA3KDM5A | |
| SCHEMBL11844336 | 0.82 | TTR (0.79) | TTRSIRT3PTPN1EYA3KDM5A | |
| SCHEMBL18743966 | 0.82 | KDM7A (0.66) | TTRSIRT3PTPN1EYA3SMPD1 | |
| SCHEMBL10670973 | 0.81 | SIRT3 (0.82) | SIRT3KDM5AKDM7AKDM4AING2 | |
| SCHEMBL10857421 | 0.81 | KDM5A (0.76) | TTRSIRT3PTPN1EYA3KDM5A | |
| SCHEMBL10853515 | 0.80 | SIRT3 (0.60) | SIRT3PTPN1EYA3KDM5AKDM7A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4565828-A | CARDIOVASCULAR DISORDERS, ANTAGONIST OF CALCIUM | SANOFI (FR) | 1986-01-21 | — | — | US | disclosed |