Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT3 | Q9NTG7 | 4/20 | 0.60 |
| ▸ | EYA3 | Q99504 | 2/20 | 0.59 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.59 |
| ▸ | KDM5A | P29375 | 8/20 | 0.59 |
| ▸ | KDM7A | Q6ZMT4 | 5/20 | 0.59 |
| ▸ | KDM4A | O75164 | 3/20 | 0.58 |
| ▸ | ING2 | Q9H160 | 1/20 | 0.58 |
| ▸ | THRA | P10827 | 2/20 | 0.56 |
| ▸ | THRB | P10828 | 2/20 | 0.56 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.55 |
| ▸ | MLNR | O43193 | 1/20 | 0.55 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.55 |
| ▸ | PHF2 | O75151 | 1/20 | 0.55 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.55 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | FYN | P06241 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10856948 | 0.91 | SIRT3 (0.59) | SIRT3EYA3PTPN1KDM5AKDM7A | |
| SCHEMBL10854519 | 0.91 | SIRT3 (0.59) | SIRT3EYA3PTPN1KDM5AKDM7A | |
| SCHEMBL11858284 | 0.88 | EYA3 (0.64) | SIRT3EYA3PTPN1KDM5AKDM7A | |
| SCHEMBL11849394 | 0.85 | SIRT3 (0.56) | SIRT3EYA3PTPN1KDM5AKDM7A | |
| SCHEMBL10855513 | 0.84 | SIRT3 (0.53) | SIRT3EYA3PTPN1KDM5AKDM7A | |
| SCHEMBL18743966 | 0.82 | KDM7A (0.66) | SIRT3EYA3PTPN1KDM5AKDM7A | |
| SCHEMBL19895690 | 0.81 | KDM5A (0.85) | SIRT3KDM5AKDM7AKDM4AING2 | |
| SCHEMBL10856111 | 0.80 | TTR (0.66) | SIRT3EYA3PTPN1KDM5AKDM7A | |
| SCHEMBL11843232 | 0.80 | EYA3 (0.77) | SIRT3EYA3PTPN1KDM5AKDM7A | |
| SCHEMBL10679251 | 0.80 | SMPD1 (0.66) | SIRT3EYA3KDM5AKDM7AKDM4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4565828-A | CARDIOVASCULAR DISORDERS, ANTAGONIST OF CALCIUM | SANOFI (FR) | 1986-01-21 | — | — | US | disclosed |