Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
| ▸ | FYN | P06241 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10852042 | 0.89 | TSHR (0.51) | TSHRPTPN1ALDH1A1LMNAKDM4E | |
| SCHEMBL11079766 | 0.72 | LMNA (0.63) | TSHRALDH1A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL14190561 | 0.71 | TSHR (0.51) | TSHRPTPN1ALDH1A1LMNAKDM4E | |
| SCHEMBL6887836 | 0.71 | TSHR (0.51) | TSHRPTPN1ALDH1A1LMNAKDM4E | |
| SCHEMBL6746376 | 0.71 | TSHR (0.50) | TSHRPTPN1ALDH1A1LMNAKDM4E | |
| SCHEMBL6885574 | 0.71 | TSHR (0.50) | TSHRPTPN1ALDH1A1LMNAKDM4E | |
| SCHEMBL11263625 | 0.70 | TSHR (0.57) | TSHRPTPN1ALDH1A1LMNAKDM4E | |
| SCHEMBL11078327 | 0.70 | ALDH1A1 (0.50) | TSHRALDH1A1LMNAKDM4EMAPT | |
| SCHEMBL14853762 | 0.69 | TSHR (0.56) | TSHRPTPN1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL11626104 | 0.69 | TSHR (0.56) | TSHRPTPN1ALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4584369-A | ANTICANCER AGENTS | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1986-04-22 | — | — | US | disclosed |
| EP-0071227-A1 | Anti-leukemic beta-glycosyl C-nucleosides | Sloan-Kettering Institute For Cancer Research (US) | 1983-02-09 | — | — | EP | disclosed |