Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MERTK | Q12866 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | GSR | P00390 | 1/20 | 0.36 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10958175 | 0.89 | PDE7A (0.40) | TDP1PDE7ALMNAHPGDSMN1; SMN2 | |
| SCHEMBL10852632 | 0.87 | TDP1 (0.60) | TDP1PDE7ALMNAHPGDSMN1; SMN2 | |
| SCHEMBL10858848 | 0.86 | TDP1 (0.43) | TDP1PDE7ALMNAHPGDSMN1; SMN2 | |
| SCHEMBL10857504 | 0.84 | MEN1 (0.42) | TDP1LMNAHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL10955246 | 0.81 | PDE7A (0.41) | TDP1PDE7ALMNAHPGDSMN1; SMN2 | |
| SCHEMBL10854591 | 0.80 | TDP1 (0.41) | TDP1PDE7ALMNAHPGDSMN1; SMN2 | |
| SCHEMBL10858278 | 0.79 | TDP1 (0.45) | TDP1LMNAHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL10854190 | 0.79 | MAPT (0.55) | TDP1PDE7ALMNAHPGDSMN1; SMN2 | |
| SCHEMBL11292229 | 0.78 | ALDH1A1 (0.34) | TDP1PDE7ALMNAHPGDSMN1; SMN2 | |
| SCHEMBL10854561 | 0.78 | ALDH1A1 (0.42) | TDP1LMNAHPGDSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4563310-A | HERBICIDES | ZOECON CORPORATION (US) | 1986-01-07 | — | — | US | disclosed |
| EP-0065374-A1 | Substituted phosphinates and phosphinothioates and their use for the control of weeds | ZOECON CORPORATION (US) | 1982-11-24 | — | — | EP | disclosed |