Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MERTK | Q12866 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | RAF1 | P04049 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
| ▸ | PPOX | P50336 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10858278 | 0.88 | TDP1 (0.45) | TDP1TSHRMAPTPOLBALDH1A1 | |
| SCHEMBL10856940 | 0.86 | TDP1 (0.43) | TDP1MAPK1TSHRMAPTALDH1A1 | |
| SCHEMBL10852632 | 0.86 | TDP1 (0.60) | TDP1MAPK1TSHRMAPTALDH1A1 | |
| SCHEMBL11044970 | 0.81 | TDP1 (0.42) | TDP1MAPK1TSHRMAPTPOLB | |
| SCHEMBL11292229 | 0.80 | ALDH1A1 (0.34) | TDP1MAPK1MAPTPOLBALDH1A1 | |
| SCHEMBL10854101 | 0.79 | TSHR (0.51) | TDP1MAPK1TSHRMAPTPOLB | |
| SCHEMBL11152258 | 0.79 | TSHR (0.61) | TDP1MAPK1TSHRMAPTPOLB | |
| SCHEMBL11781925 | 0.78 | TDP1 (0.50) | TDP1MAPK1TSHRMAPTPOLB | |
| SCHEMBL11155633 | 0.78 | TSHR (0.47) | TDP1MAPK1TSHRMAPTPOLB | |
| SCHEMBL10884723 | 0.78 | TDP1 (0.41) | TDP1MAPK1TSHRMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4563310-A | HERBICIDES | ZOECON CORPORATION (US) | 1986-01-07 | — | — | US | disclosed |
| EP-0065374-A1 | Substituted phosphinates and phosphinothioates and their use for the control of weeds | ZOECON CORPORATION (US) | 1982-11-24 | — | — | EP | disclosed |