Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | MGLL | Q99685 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9344584 | 0.85 | GABRA1 (0.46) | GABRA1GABRB2MAPTALDH1A1NPSR1 | |
| SCHEMBL10860049 | 0.81 | GABRA1 (0.35) | GABRA1GABRB2MAPTALDH1A1NPSR1 | |
| SCHEMBL8926614 | 0.73 | GABRA1 (0.37) | GABRA1GABRB2MAPTALDH1A1NPSR1 | |
| SCHEMBL8967764 | 0.73 | GABRA1 (0.37) | GABRA1GABRB2MAPTALDH1A1NPSR1 | |
| SCHEMBL11610528 | 0.72 | GABRA1 (0.36) | GABRA1GABRB2MAPTALDH1A1 | |
| Ethylbenzene SCHEMBL28174765 | 0.72 | TP53 (0.58) | MAPTALDH1A1L3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL11806035 | 0.71 | GABRA1 (0.44) | GABRA1GABRB2MAPTALDH1A1NPSR1 | |
| SCHEMBL8898679 | 0.71 | GABRA1 (0.35) | GABRA1GABRB2MAPTALDH1A1 | |
| Phosphonic Acid SCHEMBL649964 | 0.70 | GABRA1 (0.52) | GABRA1GABRB2MAPTALDH1A1NPSR1 | |
| SCHEMBL28463979 | 0.70 | LIPG (0.33) | GABRA1GABRB2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4579720-A | USING HYDROXYMETHANE DIPHOSPHONIC ACID | PLAINS CHEMICAL DEVELOPMENT CO. (US) | 1986-04-01 | — | — | US | disclosed |
| US-4440646-A | HYDROXY OR HALOALKANEPHOSPHONATES | PLAINS CHEMICAL DEVELOPMENT CO. (US) | 1984-04-03 | — | — | US | disclosed |
| EP-0015370-B1 | DIPHOSPHONATE OR PHOSPHATE-PHOSPHONATE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SYMPHAR S.A. (CH) | 1983-01-12 | — | — | EP | disclosed |