Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 1/20 | 0.57 |
| ▸ | FLT4 | P35916 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 6/20 | 0.53 |
| ▸ | NPC1 | O15118 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | CASP3 | P42574 | 1/20 | 0.53 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.53 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.53 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10856090 | 0.92 | CDK2 (0.61) | CDK2FLT4RAB9ANPC1MEN1 | |
| SCHEMBL10852567 | 0.91 | CDK2 (0.64) | CDK2FLT4RAB9ANPC1MEN1 | |
| SCHEMBL10756947 | 0.90 | CDK2 (0.57) | CDK2FLT4RAB9ANPC1MEN1 | |
| SCHEMBL10855620 | 0.89 | CDK2 (0.56) | CDK2FLT4RAB9ANPC1MEN1 | |
| SCHEMBL10987238 | 0.86 | CDK2 (0.75) | CDK2FLT4RAB9ANPC1MEN1 | |
| SCHEMBL10853890 | 0.83 | NAMPT (0.52) | RAB9AMEN1KMT2AMAPTPKM | |
| SCHEMBL10852311 | 0.83 | CDK2 (0.52) | CDK2FLT4RAB9ANPC1MEN1 | |
| SCHEMBL10854328 | 0.83 | CDK2 (0.52) | CDK2FLT4RAB9ANPC1MEN1 | |
| SCHEMBL10857079 | 0.82 | RAB9A (0.57) | CDK2FLT4RAB9ANPC1MEN1 | |
| SCHEMBL10753478 | 0.81 | CDK2 (0.52) | CDK2FLT4RAB9ANPC1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4565826-A | HYPOTENSIVE, CARDIONASCULAR, ANTIULCER, ANTISECRETORY, GASTROINTESTINAL DISORDERS | WILLIAM H. RORER, INC. (US) | 1986-01-21 | — | — | US | disclosed |
| US-4436911-A | HYPOTENSIVE, ANTISPASMODIC, ANTIULCER, ANTIPARASITIC | WILLIAM H. RORER, INC. (US) | 1984-03-13 | — | — | US | disclosed |