Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.57 |
| ▸ | NPC1 | O15118 | 5/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | CDK2 | P24941 | 1/20 | 0.52 |
| ▸ | FLT4 | P35916 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | AHR | P35869 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10756618 | 0.88 | RAB9A (0.54) | RAB9ANPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL10855620 | 0.84 | CDK2 (0.56) | RAB9ANPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL10857089 | 0.84 | RAB9A (0.54) | RAB9ANPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL10857581 | 0.84 | RAB9A (0.54) | RAB9ANPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL14538107 | 0.84 | NPC1 (0.51) | RAB9ANPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL30633570 | 0.84 | RAB9A (0.68) | RAB9ANPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL7785654 | 0.84 | RAB9A (0.68) | RAB9ANPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL10857086 | 0.82 | CDK2 (0.57) | RAB9ANPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL10854328 | 0.81 | CDK2 (0.52) | RAB9ANPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL10852311 | 0.81 | CDK2 (0.52) | RAB9ANPC1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4565826-A | HYPOTENSIVE, CARDIONASCULAR, ANTIULCER, ANTISECRETORY, GASTROINTESTINAL DISORDERS | WILLIAM H. RORER, INC. (US) | 1986-01-21 | — | — | US | disclosed |
| US-4436911-A | HYPOTENSIVE, ANTISPASMODIC, ANTIULCER, ANTIPARASITIC | WILLIAM H. RORER, INC. (US) | 1984-03-13 | — | — | US | disclosed |