Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | TBXAS1 | P24557 | 9/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9768497 | 0.88 | TBXAS1 (0.60) | KMT2ATBXAS1KDM4EPKMLMNA | |
| Hydrochloric Acid SCHEMBL10859852 | 0.87 | TBXAS1 (0.59) | KMT2ATBXAS1KDM4EPKMLMNA | |
| SCHEMBL10891760 | 0.81 | TBXAS1 (0.49) | KMT2ATBXAS1KDM4EPKMLMNA | |
| SCHEMBL10861223 | 0.80 | KMT2A (0.53) | KMT2ATBXAS1KDM4EPKMLMNA | |
| SCHEMBL10859502 | 0.80 | TBXAS1 (0.52) | KMT2ATBXAS1KDM4ELMNAALDH1A1 | |
| Hydrochloric Acid SCHEMBL10888060 | 0.79 | KDM4E (0.52) | KMT2ATBXAS1KDM4EPKMLMNA | |
| SCHEMBL10888480 | 0.77 | TBXAS1 (0.49) | KMT2ATBXAS1KDM4EPKMLMNA | |
| SCHEMBL10955620 | 0.76 | TBXAS1 (0.81) | KMT2ATBXAS1ALDH1A1 | |
| SCHEMBL10861251 | 0.75 | KMT2A (0.44) | KMT2AKDM4ELMNAHTTSMN1; SMN2 | |
| SCHEMBL5124845 | 0.75 | MAPT (0.44) | KMT2AKDM4EPKMLMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4590203-A | Derivatives of thiophene-2-carboxylic acid and their pharmaceutically acceptable acid or base addition salts and use in treatment of conditions caused by thromboxane A2 | LAEVOSAN-GESELLSCHAFT M.B.H. & CO. KG (AT) | 1986-05-20 | — | — | US | claimed |
| US-4590203-A | Derivatives of thiophene-2-carboxylic acid and their pharmaceutically acceptable acid or base addition salts and use in treatment of conditions caused by thromboxane A2 | LAEVOSAN-GESELLSCHAFT M.B.H. & CO. KG (AT) | 1986-05-20 | — | — | US | disclosed |