Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 8/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10888480 | 0.91 | TBXAS1 (0.49) | TBXAS1KMT2AKDM4EPKMPOLB | |
| Hydrochloric Acid SCHEMBL10888060 | 0.88 | KDM4E (0.52) | TBXAS1KMT2AKDM4EPKMPOLB | |
| SCHEMBL10891544 | 0.82 | TBXAS1 (0.55) | TBXAS1KMT2AKDM4EALDH1A1LMNA | |
| SCHEMBL10887353 | 0.82 | TBXAS1 (0.47) | TBXAS1KMT2AKDM4EPKMPOLB | |
| SCHEMBL10857097 | 0.81 | KMT2A (0.51) | TBXAS1KMT2AKDM4EPKMPOLB | |
| Hydrochloric Acid SCHEMBL11106558 | 0.81 | KDM4E (0.51) | TBXAS1KMT2AKDM4EPKMPOLB | |
| SCHEMBL9768497 | 0.79 | TBXAS1 (0.60) | TBXAS1KMT2AKDM4EPKMPOLB | |
| SCHEMBL10861223 | 0.78 | KMT2A (0.53) | TBXAS1KMT2AKDM4EPKMPOLB | |
| Hydrochloric Acid SCHEMBL10859852 | 0.78 | TBXAS1 (0.59) | TBXAS1KMT2AKDM4EPKMPOLB | |
| SCHEMBL10889824 | 0.76 | GAA (0.36) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0109381-B1 | THIOPHENE-2-CARBOXYLIC-ACID DERIVATIVES AND PROCESS FOR THEIR PREPARATION | Laevosan-Gesellschaft m.b.H. (AT) | 1986-07-30 | — | — | EP | claimed |
| EP-0109381-A1 | Thiophene-2-carboxylic-acid derivatives and process for their preparation | Laevosan-Gesellschaft m.b.H. (AT) | 1984-05-23 | — | — | EP | claimed |
| EP-0109381-B1 | THIOPHENE-2-CARBOXYLIC-ACID DERIVATIVES AND PROCESS FOR THEIR PREPARATION | Laevosan-Gesellschaft m.b.H. (AT) | 1986-07-30 | — | — | EP | disclosed |
| EP-0109381-A1 | Thiophene-2-carboxylic-acid derivatives and process for their preparation | Laevosan-Gesellschaft m.b.H. (AT) | 1984-05-23 | — | — | EP | disclosed |