Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | MYC | P01106 | 4/20 | 0.45 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MLYCD | O95822 | 1/20 | 0.42 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL225760 | 0.90 | ALDH1A1 (0.50) | ALDH1A1ALOX15MYCNR4A1L3MBTL1 | |
| SCHEMBL8048603 | 0.80 | ALDH1A1 (0.61) | ALDH1A1ALOX15MYCNR4A1L3MBTL1 | |
| SCHEMBL2492855 | 0.77 | NPC1 (0.68) | ALDH1A1ALOX15MYCNR4A1L3MBTL1 | |
| SCHEMBL29467270 | 0.77 | NPC1 (0.68) | ALDH1A1ALOX15MYCNR4A1L3MBTL1 | |
| Nesosteine SCHEMBL1525263 | 0.77 | ALDH1A1 (0.55) | ALDH1A1ALOX15L3MBTL1DPP4 | |
| Nesosteine SCHEMBL11066850 | 0.75 | ALDH1A1 (0.54) | ALDH1A1ALOX15L3MBTL1DPP4 | |
| SCHEMBL227731 | 0.75 | NPC1 (0.71) | ALDH1A1ALOX15MYCNR4A1L3MBTL1 | |
| SCHEMBL1715918 | 0.75 | NPC1 (0.71) | ALDH1A1ALOX15MYCNR4A1L3MBTL1 | |
| SCHEMBL26134988 | 0.75 | NPC1 (0.70) | ALDH1A1ALOX15NPC1 | |
| SCHEMBL3808106 | 0.74 | ALDH1A1 (0.70) | ALDH1A1ALOX15MYCNR4A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4575496-A | ANTIBIOTICS; SELECTIVE THERAPY OF RESOIRATORY TRACT | CAMILLO CORVI S.P.A. (IT) | 1986-03-11 | — | — | US | claimed |
| US-4575496-A | ANTIBIOTICS; SELECTIVE THERAPY OF RESOIRATORY TRACT | CAMILLO CORVI S.P.A. (IT) | 1986-03-11 | — | — | US | disclosed |