SCHEMBL10858461

SCHEMBL10858461

Fc1ccccc1C(F)(F)ON(F)F

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KCNN4 O15554 5/20 0.34
KCNE1 P15382 1/20 0.31
KCNQ1 P51787 1/20 0.31
SLC22A12 Q96S37 1/20 0.31
ACHE P22303 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15744424 0.74 CCR6 (0.36) KCNN4KCNE1KCNQ1SLC22A12ACHE
SCHEMBL554230 0.71 KCNN4 (0.37) KCNN4KCNE1KCNQ1SLC22A12ACHE
SCHEMBL21474301 0.71 KCNN4 (0.38) KCNN4KCNE1KCNQ1SLC22A12
SCHEMBL2525080 0.70 KCNN4 (0.44) KCNN4KCNE1KCNQ1SLC22A12ACHE
SCHEMBL888536 0.69 KCNN4 (0.33) KCNN4KCNE1KCNQ1SLC22A12
SCHEMBL29466225 0.69 SLC22A12 (0.46) KCNN4SLC22A12ACHE
SCHEMBL169053 0.69 SLC22A12 (0.46) KCNN4SLC22A12ACHE
SCHEMBL10602905 0.69 KCNN4 (0.42) KCNN4KCNE1KCNQ1SLC22A12ACHE
Water SCHEMBL27483772 0.68 KCNN4 (0.33) KCNN4
Hydrochloric Acid SCHEMBL9803342 0.68 KCNN4 (0.33) KCNN4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4629689-A Binding assay with amplified read-out and gas-phase detection ALLIED CORPORATION (US) 1986-12-16 US disclosed
EP-0173055-A2 Binding assay with amplified read-out and gas-phase detection ALLIED CORPORATION (US) 1986-03-05 EP disclosed