SCHEMBL888536

SCHEMBL888536

FON(F)C(F)(F)c1ccccc1F

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
KCNN4 O15554 5/20 0.33
KCNE1 P15382 1/20 0.30
KCNQ1 P51787 1/20 0.30
SLC22A12 Q96S37 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL9803342 0.98 KCNN4 (0.33) KCNN4
Water SCHEMBL27483772 0.98 KCNN4 (0.33) KCNN4
SCHEMBL554230 0.79 KCNN4 (0.37) KCNN4KCNE1KCNQ1SLC22A12
SCHEMBL7633389 0.71 AR (0.36) KCNN4
SCHEMBL10858461 0.69 KCNN4 (0.34) KCNN4KCNE1KCNQ1SLC22A12
SCHEMBL2525080 0.69 KCNN4 (0.44) KCNN4KCNE1KCNQ1SLC22A12
SCHEMBL29466225 0.68 SLC22A12 (0.46) KCNN4SLC22A12
SCHEMBL169053 0.68 SLC22A12 (0.46) KCNN4SLC22A12
SCHEMBL10602905 0.68 KCNN4 (0.42) KCNN4KCNE1KCNQ1SLC22A12
Ammonia Solution, Strong SCHEMBL2163470 0.66 SLC22A12 (0.44) KCNN4SLC22A12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022122846-A1 ETHODS OF DETECTING ALDEHYDES IN SAMPLES LONZA LTD (CH) 2022-06-16 WO claimed
CN-114414696-A Kit and method for determining multiple estrogens in dried blood tablets 合肥歆智医疗器械有限公司 2022-04-29 CN claimed
US-12180460-B2 Long-living, thermotolerant yeast and use thereof in producing a fermented beverage DUVEL MOORTGAT NV (BE) 2024-12-31 US disclosed
EP-4067896-B1 METHOD FOR DETERMINING RESIDUAL ALDEHYDES RELEASABLE FROM A SYRINGE NUOVA OMPI SRL (IT) 2024-12-25 EP disclosed
US-20240165283-A1 Method for extracting aldehydes from the adhesive of a syringe NUOVA OMPI S.R.L. (IT) 2024-05-23 US disclosed
CN-117480189-A Method for extracting aldehyde from adhesive of syringe 诺瓦欧姆皮埃有限公司 2024-01-30 CN disclosed
US-20230312809-A1 LIQUID FORMULATION COMPRISING AN ALDEHYDE SCAVENGER Ferline SA (CH) 2023-10-05 US disclosed
US-20230174923-A1 LONG-LIVING, THERMOTOLERANT YEAST AND USE THEREOF IN PRODUCING A FERMENTED BEVERAGE DUVEL MOORTGAT NV (BE) 2023-06-08 US disclosed
EP-4157915-A1 LIQUID FORMULATION COMPRISING AN ALDEHYDE SCAVENGER Ferline SA (CH) 2023-04-05 EP disclosed
EP-4146786-A1 LONG-LIVING, THERMOTOLERANT YEAST AND USE THEREOF IN PRODUCING A FERMENTED BEVERAGE Duvel Moortgat NV (BE) 2023-03-15 EP disclosed
CN-115698118-A Liquid formulations comprising aldehyde scavengers 佛莱恩股份公司 2023-02-03 CN disclosed
WO-2006045514-A1 3-ARYLAMINO PYRIDINE DERIVATIVES APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (NL) 2006-05-04 WO disclosed
US-20060020440-A1 Molecular flux rates through critical pathways measured by stable isotope labeling in vivo, as biomarkers of drug action and disease activity THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2006-01-26 US disclosed
US-20050288183-A1 Sorbent collector material based on polyorganosiloxane GERSTEL SYSTEMTECHNIK GMBH & CO. KG (DE) 2005-12-29 US disclosed
EP-1607134-A1 Polyorganosiloxane-based sorbent trap material Gerstel Systemtechnik GmbH & Co. KG (DE) 2005-12-21 EP disclosed
US-20050255509-A1 In vivo measurement of the relative fluxes through ribonucleotide reductase vs. deoxyribonucleoside pathways using isotopes KINEMED, INC. (US) 2005-11-17 US disclosed
US-20050202406-A1 Method for high-throughput screening of compounds and combinations of compounds for discovery and quantification of actions, particularly unanticipated therapeutic or toxic actions, in biological systems THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2005-09-15 US disclosed
WO-2005081943-A2 MOLECULAR FLUX RATES THROUGH CRITICAL PATHWAYS MEASURED BY STABLE ISOTOPE LABELING IN VIVO, AS BIOMARKERS OF DRUG ACTION AND DISEASE ACTIVITY THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2005-09-09 WO disclosed
WO-2005051434-A1 METHOD FOR HIGH-THROUGHPUT SCREENING OF COMPOUNDS AND COMBINATIONS OF COMPOUNDS FOR DISCOVERY AND QUANTIFICATION OF ACTIONS, PARTICULARLY UNANTICIPATED THERAPEUTIC OR TOXIC ACTIONS, IN BIOLOGICAL SYSTEMS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2005-06-09 WO disclosed
WO-1988006732-A1 TAGGED BINDING REAGENTS AND METHODS FOR DETECTING TARGET ANALYTES ALLIED CORPORATION (US) 1988-09-07 WO disclosed