Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 6/20 | 0.37 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.33 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.32 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | KIF11 | P52732 | 1/20 | 0.31 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.30 |
| ▸ | FEN1 | P39748 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL888536 | 0.79 | KCNN4 (0.33) | KCNN4SLC22A12KCNE1KCNQ1 | |
| SCHEMBL4458987 | 0.78 | IDO1 (0.38) | KCNN4KCNE1KCNQ1NFE2L2 | |
| Water SCHEMBL27483772 | 0.77 | KCNN4 (0.33) | KCNN4 | |
| SCHEMBL7633389 | 0.77 | AR (0.36) | KCNN4 | |
| Hydrochloric Acid SCHEMBL9803342 | 0.77 | KCNN4 (0.33) | KCNN4 | |
| SCHEMBL2525080 | 0.75 | KCNN4 (0.44) | KCNN4SLC22A12ACHEKCNE1KCNQ1 | |
| SCHEMBL29466225 | 0.74 | SLC22A12 (0.46) | KCNN4SLC22A12ACHEHSD11B1KIF11 | |
| SCHEMBL10602905 | 0.74 | KCNN4 (0.42) | KCNN4SLC22A12ACHEKCNE1KCNQ1 | |
| SCHEMBL169053 | 0.74 | SLC22A12 (0.46) | KCNN4SLC22A12ACHEHSD11B1KIF11 | |
| SCHEMBL7633380 | 0.73 | AR (0.33) | KCNN4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-63258452-A | — | — | None | — | — | JP | disclosed |
| CN-114015063-B | Nitro-ligand-doped zeolitic imidazolate framework material ZIF-71-clnIm x Preparation and use of | 太原理工大学 | 2023-01-10 | — | — | CN | disclosed |
| CN-114751807-A | Novel efficient preparation process of 2,3,5, 6-tetrafluorobenzyl alcohol | 忠同科技(大连)有限公司 | 2022-07-15 | — | — | CN | disclosed |
| CN-114015063-A | Nitro-ligand-doped zeolitic imidazolate framework material ZIF-71-clnImxPreparation and use of | 太原理工大学 | 2022-02-08 | — | — | CN | disclosed |
| US-8110695-B2 | Compounds and compositions containing silicon and/or other heteroatoms and/or metals and methods of making and using them | WELKER MARK E (US) | 2012-02-07 | — | — | US | disclosed |
| US-20100056801-A1 | Compounds And Compositions Containing Silicon And/Or Other Heteroatoms And/Or Metals And Methods of Making And Using Them | WELKER MARK E | 2010-03-04 | — | — | US | disclosed |
| WO-2008054718-A2 | COMPOUNDS AND COMPOSITIONS CONTAINING SILICON AND/OR OTHER HETEROATOMS AND/OR METALS AND METHODS OF MAKING AND USING THEM | WAKE FOREST UNIVERSITY (US) | 2008-05-08 | — | — | WO | disclosed |
| EP-0910380-B1 | SUBSTITUTED BENZYLIDENE INDENYL FORMAMIDES, ACETAMIDES AND PROPIONAMIDES | CELL PATHWAYS INC (US) | 2003-08-13 | — | — | EP | disclosed |
| US-6403831-B1 | 5,6-DIFLUORO-2-METHYL-1-(3,4,5-TRIMETHOXY-BENZYLIDENE)-3-(N-BE NZYL)-INDENYL ACETAMIDE; ANTITUMOR AND ANTICARCINOGENIC AGENT USED TO TREAT PRECANCEROUS LESIONS | CELL PATHWAYS, INC. | 2002-06-11 | — | — | US | disclosed |
| EP-0819000-A4 | NODULISPORIC ACID DERIVATIVES | MERCK & CO INC (US) | 2001-04-11 | — | — | EP | disclosed |
| WO-1996029073-A1 | NODULISPORIC ACID DERIVATIVES | MERCK & CO., INC. (US) | 1996-09-26 | — | — | WO | disclosed |
| EP-0452055-B1 | Surfaces with reduced protein interactions | HEWLETT PACKARD CO (US) | 1995-01-11 | — | — | EP | disclosed |
| EP-0377649-B1 | HALOGENATED SURFACE WITH REDUCED PROTEIN INTERACTION | Hewlett-Packard Company (US) | 1993-03-10 | — | — | EP | disclosed |
| US-5114768-A | Electrophoretic protein separation | HEWLETT-PACKARD COMPANY (US) | 1992-05-19 | — | — | US | disclosed |
| EP-0452055-A1 | Surfaces with reduced protein interactions | Hewlett-Packard Company (US) | 1991-10-16 | — | — | EP | disclosed |
| US-5006313-A | Halogenated surface with reduced protein interaction | HEWLETT-PACKARD COMPANY (US) | 1991-04-09 | — | — | US | disclosed |
| EP-0377649-A1 | HALOGENATED SURFACE WITH REDUCED PROTEIN INTERACTION. | HEWLETT PACKARD CO (US) | 1990-07-18 | — | — | EP | disclosed |
| WO-1989012225-A1 | HALOGENATED SURFACE WITH REDUCED PROTEIN INTERACTION | HEWLETT-PACKARD COMPANY (US) | 1989-12-14 | — | — | WO | disclosed |
| JP-S63258452-A | MONOMER CONTAINING FLUORINATED AROMATIC GROUP AND POLYMER PRODUCED THEREFROM | NIPPON SHOKUBAI KAGAKU KOGYO CO LTD | 1988-10-25 | — | — | JP | disclosed |
| US-3946063-A | 2,3,4,5,6-PENTAFLUOROBENZYL CHLOROFORMATE | PIERCE CHEMICAL COMPANY (US) | 1976-03-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100056801-A1 | Compounds And Compositions Containing Silicon And/Or Other Heteroatoms And/Or Metals And Methods of Making And Using Them | CA6, SOD1, CA1 | KCNN4 884/4885SLC22A12 976/4885ACHE 861/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.