Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | CCR1 | P32246 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | FAAH | O00519 | 1/20 | 0.50 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10858747 | 1.00 | ALDH1A1 (0.59) | ALDH1A1SMN1; SMN2KMT2AMEN1CYP3A4 | |
| SCHEMBL10857639 | 0.87 | POLB (0.61) | ALDH1A1HTTPKMLMNAFAAH | |
| SCHEMBL10857630 | 0.87 | POLB (0.61) | ALDH1A1HTTPKMLMNAFAAH | |
| SCHEMBL10859034 | 0.84 | CAPN1 (0.56) | ALDH1A1SMN1; SMN2KMT2AMEN1CYP3A4 | |
| SCHEMBL10858984 | 0.84 | CAPN1 (0.56) | ALDH1A1SMN1; SMN2KMT2AMEN1CYP3A4 | |
| SCHEMBL10859075 | 0.84 | CAPN1 (0.56) | ALDH1A1SMN1; SMN2KMT2AMEN1CYP3A4 | |
| SCHEMBL1623416 | 0.82 | KMT2A (0.66) | ALDH1A1SMN1; SMN2KMT2AMEN1HTT | |
| SCHEMBL1623417 | 0.82 | KMT2A (0.66) | ALDH1A1SMN1; SMN2KMT2AMEN1HTT | |
| SCHEMBL14705776 | 0.81 | LMNA (0.55) | ALDH1A1SMN1; SMN2KMT2AMEN1CYP3A4 | |
| SCHEMBL10856911 | 0.81 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2KMT2AMEN1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4596803-A | Treating myocardial infarction | NIPPON CHEMIPHAR CO., LTD. (JP) | 1986-06-24 | — | — | US | disclosed |
| US-4507297-A | MYOCARDIAL INFARCTION | NIPPON CHEMIPHAR CO., LTD. (JP) | 1985-03-26 | — | — | US | disclosed |