Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 9/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | APP | P05067 | 1/20 | 0.49 |
| ▸ | MMP2 | P08253 | 1/20 | 0.49 |
| ▸ | MMP9 | P14780 | 1/20 | 0.49 |
| ▸ | MMP8 | P22894 | 1/20 | 0.49 |
| ▸ | MMP13 | P45452 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | CLK1 | P49759 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2118962 | 0.81 | KAT8 (0.59) | SNCAMAPTALDH1A1KMT2AAPP | |
| SCHEMBL1228438 | 0.81 | KAT8 (0.59) | SNCAMAPTALDH1A1KMT2AAPP | |
| SCHEMBL6116681 | 0.80 | SNCA (0.53) | SNCAMAPTALDH1A1KMT2AAPP | |
| SCHEMBL6116675 | 0.80 | SNCA (0.53) | SNCAMAPTALDH1A1KMT2AAPP | |
| SCHEMBL537900 | 0.79 | SNCA (0.57) | SNCAMAPTALDH1A1KMT2AAPP | |
| SCHEMBL3447907 | 0.79 | SNCA (0.57) | SNCAMAPTALDH1A1KMT2AAPP | |
| SCHEMBL2243418 | 0.76 | MMP13 (0.63) | MAPTALDH1A1KMT2AAPPMMP2 | |
| SCHEMBL3201875 | 0.76 | MAPT (0.55) | SNCAMAPTALDH1A1KMT2AAPP | |
| SCHEMBL3201868 | 0.76 | MAPT (0.55) | SNCAMAPTALDH1A1KMT2AAPP | |
| SCHEMBL10860786 | 0.75 | MAPT (0.48) | MAPTALDH1A1KMT2AMEN1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4590275-A | CYTOTOXIC, ANTITUMOR, ANTIVIRAL AGENTS | COMMONWEALTH OF PUERTO RICO (US) | 1986-05-20 | — | — | US | disclosed |