Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 7/20 | 0.54 |
| ▸ | MAPT | P10636 | 7/20 | 0.54 |
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | NPC1 | O15118 | 5/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | APP | P05067 | 1/20 | 0.51 |
| ▸ | INSR | P06213 | 1/20 | 0.51 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3447907 | 1.00 | SNCA (0.57) | SNCARAB9AMAPTMEN1KMT2A | |
| SCHEMBL10619184 | 0.88 | SNCA (0.65) | SNCARAB9AMAPTMEN1KMT2A | |
| SCHEMBL6496513 | 0.86 | SNCA (0.57) | SNCARAB9AMAPTMEN1KMT2A | |
| SCHEMBL6496514 | 0.86 | SNCA (0.57) | SNCARAB9AMAPTMEN1KMT2A | |
| SCHEMBL6115915 | 0.84 | MAPT (0.54) | SNCARAB9AMAPTMEN1KMT2A | |
| SCHEMBL6115910 | 0.84 | MAPT (0.54) | SNCARAB9AMAPTMEN1KMT2A | |
| SCHEMBL6116681 | 0.83 | SNCA (0.53) | SNCARAB9AMAPTMEN1KMT2A | |
| SCHEMBL6116675 | 0.83 | SNCA (0.53) | SNCARAB9AMAPTMEN1KMT2A | |
| SCHEMBL6117521 | 0.83 | RAB9A (0.46) | SNCARAB9AMAPTMEN1KMT2A | |
| SCHEMBL6117515 | 0.83 | RAB9A (0.46) | SNCARAB9AMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2414355-A2 | FLUORESCENT CELLULAR MARKERS | Zayas, Beatriz (US) | 2012-02-08 | — | — | EP | claimed |
| WO-2010135751-A2 | FLUORESCENT CELLULAR MARKERS | BEATRIZ ZAYAS BEATRIZ (US) | 2010-11-25 | — | — | WO | claimed |
| US-20100256378-A1 | FLUORESCENT CELLULAR MARKERS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2010-10-07 | — | — | US | claimed |
| US-20050260126-A1 | Diagnostic probes and remedies for diseases with accumulation of prion protein, and stains for prion protein | BF RESEARCH INSTITUTE (JP) | 2005-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050260126-A1 | Diagnostic probes and remedies for diseases with accumulation of prion protein, and stains for prion protein | PRNP, PRPH, PCNP | SNCA 20/4885RAB9A 1787/4885MAPT 7/4885 |
| US-20100256378-A1 | FLUORESCENT CELLULAR MARKERS | AIFM1, CASP3, BAX | SNCA 1855/4885RAB9A 862/4885MAPT 3510/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.