Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CES1 | P23141 | 6/20 | 0.41 |
| ▸ | CES2 | O00748 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA4 | P22748 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27652461 | 0.78 | LMNA (0.44) | LMNACES1CES2ALDH1A1TSHR | |
| SCHEMBL9718676 | 0.75 | LMNA (0.46) | LMNACES1CES2ALDH1A1TSHR | |
| SCHEMBL8765171 | 0.73 | LMNA (0.41) | LMNACES1CES2ALDH1A1TSHR | |
| SCHEMBL3664914 | 0.72 | CES1 (0.45) | LMNACES1CES2ALDH1A1TSHR | |
| SCHEMBL11188605 | 0.71 | CES1 (0.46) | LMNACES1CES2ALDH1A1TSHR | |
| SCHEMBL813023 | 0.71 | LMNA (0.46) | LMNACES1CES2ALDH1A1TSHR | |
| SCHEMBL1446381 | 0.69 | LMNA (0.44) | LMNACES1CES2ALDH1A1TSHR | |
| SCHEMBL9052323 | 0.69 | LMNA (0.44) | LMNACES1CES2ALDH1A1TSHR | |
| SCHEMBL1431419 | 0.69 | LMNA (0.44) | LMNACES1CES2ALDH1A1TSHR | |
| SCHEMBL29118952 | 0.69 | LMNA (0.49) | LMNACES1CES2ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0190945-A2 | Herbicidal propylene oxide derivatives | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1986-08-13 | — | — | EP | disclosed |