Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CES2 | O00748 | 4/20 | 0.45 |
| ▸ | CES1 | P23141 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9004751 | 0.87 | LMNA (0.40) | LMNACES2CES1MAPTPOLB | |
| SCHEMBL9718661 | 0.87 | LMNA (0.40) | LMNACES2CES1MAPTPOLB | |
| SCHEMBL9004904 | 0.82 | LMNA (0.36) | LMNACES2CES1POLBALDH1A1 | |
| SCHEMBL9314611 | 0.81 | ALDH1A1 (0.36) | LMNACES2CES1POLBALDH1A1 | |
| SCHEMBL9004647 | 0.81 | ALDH1A1 (0.36) | LMNACES2CES1POLBALDH1A1 | |
| SCHEMBL9004975 | 0.79 | LMNA (0.38) | LMNAALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL9314643 | 0.79 | LMNA (0.38) | LMNAALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL27652461 | 0.78 | LMNA (0.44) | LMNACES2CES1MAPTPOLB | |
| SCHEMBL9004822 | 0.78 | LMNA (0.37) | LMNACES2CES1MAPTALDH1A1 | |
| SCHEMBL9315381 | 0.78 | LMNA (0.37) | LMNACES2CES1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5147901-A | PROPIONPHENONE DERIVATIVES AS PHOTOINITIATORS FOR PHOTOPOLYMERIZATION | CIBA-GEIGY CORPORATION (US) | 1992-09-15 | — | — | US | disclosed |
| EP-0108037-B1 | PROPIOPHENONE DERIVATIVES AS PHOTOINITIATORS IN THE PHOTOPOLYMERIZATION | CIBA-GEIGY AG (CH) | 1989-06-07 | — | — | EP | disclosed |
| US-4795766-A | OF ETHYLENICALLY UNSATURATED COMPOUNDS; PRINTING INK | CIBA-GEIGY CORPORATION (US) | 1989-01-03 | — | — | US | disclosed |
| EP-0108037-A2 | Propiophenone derivatives as photoinitiators in the photopolymerization | CIBA-GEIGY AG (CH) | 1984-05-09 | — | — | EP | disclosed |