Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | TOP1 | P11387 | 8/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | GSK3A | P49840 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.36 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10856684 | 0.90 | KDM4E (0.35) | KCNH2TOP1PIM1GSK3AGSK3B | |
| SCHEMBL6897930 | 0.85 | KDM4E (0.49) | KCNH2PIM1GSK3AGSK3BPIM3 | |
| SCHEMBL6902945 | 0.85 | PLAT (0.38) | — | |
| SCHEMBL6904311 | 0.81 | KMT2A (0.39) | — | |
| SCHEMBL10911645 | 0.77 | KCNH2 (0.47) | KCNH2TOP1PIM1GSK3AGSK3B | |
| SCHEMBL6903139 | 0.75 | RXFP1 (0.41) | — | |
| SCHEMBL10529388 | 0.74 | KCNH2 (0.68) | KCNH2TOP1 | |
| SCHEMBL11020049 | 0.71 | PIM1 (0.41) | KCNH2TOP1PIM1GSK3AGSK3B | |
| SCHEMBL10771130 | 0.69 | NPC1 (0.37) | — | |
| SCHEMBL10859996 | 0.68 | KCNH2 (0.53) | KCNH2TOP1PIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0183129-A1 | Quinolonecarboxylic acid derivatives | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1986-06-04 | — | — | EP | disclosed |