Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAT | P00750 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.37 |
| ▸ | HPGD | P15428 | 6/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | TOP2A | P11388 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6897930 | 0.89 | KDM4E (0.49) | PLATALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL6904311 | 0.85 | KMT2A (0.39) | PLATALDH1A1KDM4EHPGDTSHR | |
| SCHEMBL10860469 | 0.85 | KCNH2 (0.43) | — | |
| SCHEMBL10771130 | 0.84 | NPC1 (0.37) | PLATALDH1A1HSD17B10LMNANPSR1 | |
| SCHEMBL10856684 | 0.84 | KDM4E (0.35) | ALDH1A1KDM4EHPGDHSD17B10LMNA | |
| SCHEMBL6903139 | 0.78 | RXFP1 (0.41) | ALDH1A1KDM4EHPGDHSD17B10LMNA | |
| SCHEMBL6903795 | 0.76 | CYP1A2 (0.47) | ALDH1A1KDM4EHPGDHSD17B10LMNA | |
| SCHEMBL9674400 | 0.75 | PIM1 (0.42) | ALDH1A1KDM4EHPGDHSD17B10LMNA | |
| SCHEMBL9674720 | 0.75 | KDM4E (0.39) | ALDH1A1KDM4EHPGDHSD17B10LMNA | |
| SCHEMBL9234131 | 0.74 | PIM1 (0.39) | ALDH1A1KDM4EHPGDHSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401829-A4 | NOVEL HETEROCYCLIC ANTIBACTERIAL COMPOUNDS | MICROBIOTIX INC (US) | 2004-10-27 | — | — | EP | disclosed |
| EP-1401829-A1 | NOVEL HETEROCYCLIC ANTIBACTERIAL COMPOUNDS | Microbiotix, Inc. (US) | 2004-03-31 | — | — | EP | disclosed |
| WO-2002102792-A1 | NOVEL HETEROCYCLIC ANTIBACTERIAL COMPOUNDS | MICROBIOTIX, INC. (US) | 2002-12-27 | — | — | WO | disclosed |