Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.49 |
| ▸ | HPGD | P15428 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.49 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | CLK2 | P49760 | 1/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | GSK3A | P49840 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.35 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6902945 | 0.89 | PLAT (0.38) | KDM4EHPGDALDH1A1HSD17B10PMP22 | |
| SCHEMBL10860469 | 0.85 | KCNH2 (0.43) | KCNH2PIM1GSK3AGSK3BPIM3 | |
| SCHEMBL10856684 | 0.84 | KDM4E (0.35) | KDM4EHPGDALDH1A1HSD17B10PMP22 | |
| SCHEMBL6904311 | 0.82 | KMT2A (0.39) | KDM4EHPGDALDH1A1CYP2C19PLAT | |
| SCHEMBL9675600 | 0.78 | KDM4E (0.54) | KDM4EHPGDALDH1A1HSD17B10PMP22 | |
| SCHEMBL10771130 | 0.75 | NPC1 (0.37) | ALDH1A1HSD17B10PLATMEN1KMT2A | |
| SCHEMBL6903139 | 0.75 | RXFP1 (0.41) | KDM4EHPGDALDH1A1HSD17B10POLB | |
| SCHEMBL6784057 | 0.75 | KCNH2 (0.66) | KDM4EHPGDALDH1A1HSD17B10PMP22 | |
| SCHEMBL10958351 | 0.75 | KDM4E (0.54) | KDM4EHPGDALDH1A1HSD17B10PMP22 | |
| SCHEMBL10655162 | 0.74 | KDM4E (0.80) | KDM4EHPGDALDH1A1HSD17B10PMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401829-A4 | NOVEL HETEROCYCLIC ANTIBACTERIAL COMPOUNDS | MICROBIOTIX INC (US) | 2004-10-27 | — | — | EP | disclosed |
| EP-1401829-A1 | NOVEL HETEROCYCLIC ANTIBACTERIAL COMPOUNDS | Microbiotix, Inc. (US) | 2004-03-31 | — | — | EP | disclosed |
| WO-2002102792-A1 | NOVEL HETEROCYCLIC ANTIBACTERIAL COMPOUNDS | MICROBIOTIX, INC. (US) | 2002-12-27 | — | — | WO | disclosed |