Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | GLA | P06280 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RAD52 | P43351 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11478959 | 0.83 | ALDH1A1 (0.50) | KDM4EGLAMEN1KMT2ALMNA | |
| SCHEMBL23657198 | 0.82 | KDM4E (0.62) | KDM4EGLAMEN1KMT2ALMNA | |
| SCHEMBL13180324 | 0.82 | KDM4E (0.62) | KDM4EGLAMEN1KMT2ALMNA | |
| SCHEMBL23657255 | 0.82 | KDM4E (0.62) | KDM4EGLAMEN1KMT2ALMNA | |
| SCHEMBL14538079 | 0.82 | KMT2A (0.60) | KDM4EMEN1KMT2AMAPTTSHR | |
| SCHEMBL11131278 | 0.81 | KDM4E (0.58) | KDM4EGLAMEN1KMT2ALMNA | |
| Hydrochloric Acid SCHEMBL8604668 | 0.81 | KDM4E (0.60) | KDM4EGLAMEN1KMT2ALMNA | |
| SCHEMBL3060825 | 0.80 | MEN1 (0.64) | KDM4EMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL11480838 | 0.80 | MEN1 (0.64) | KDM4EMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL25493043 | 0.79 | SMN1; SMN2 (0.65) | KDM4EGLAMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4593027-A | 3-aryl-7-chloro-3,4-dihydroacridine-1,9(2H,10H)-dione 1-oximes and 1-hydrazone derivatives, their salts, a process for their preparation, agents containing them and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-06-03 | — | — | US | disclosed |
| US-4235899-A | ANTIPROTOZOA AGENTS ESPECIALLY AGAINST TRICHOMONAS | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-11-25 | — | — | US | disclosed |