Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | RAD52 | P43351 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10861144 | 0.83 | KDM4E (0.60) | ALDH1A1KDM4EKMT2AHTTLMNA | |
| SCHEMBL21469813 | 0.81 | TP53 (0.55) | ALDH1A1KDM4EKMT2AHTTLMNA | |
| SCHEMBL14538079 | 0.80 | KMT2A (0.60) | KDM4EKMT2AHTTMEN1SMN1; SMN2 | |
| SCHEMBL15296753 | 0.79 | SMN1; SMN2 (0.61) | ALDH1A1KDM4EKMT2AHTTLMNA | |
| SCHEMBL11480838 | 0.79 | MEN1 (0.64) | ALDH1A1KDM4EKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL3060825 | 0.79 | MEN1 (0.64) | ALDH1A1KDM4EKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL1361162 | 0.78 | MAPT (0.64) | ALDH1A1KDM4EKMT2AHTTLMNA | |
| SCHEMBL21537500 | 0.77 | ALDH1A1 (0.47) | ALDH1A1KDM4EKMT2AHTTLMNA | |
| Hydrochloric Acid SCHEMBL29215641 | 0.77 | KMT2A (0.61) | ALDH1A1KDM4EKMT2AHTTMEN1 | |
| SCHEMBL12227800 | 0.76 | ALDH1A1 (0.46) | ALDH1A1KDM4EKMT2AHTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4235899-A | ANTIPROTOZOA AGENTS ESPECIALLY AGAINST TRICHOMONAS | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-11-25 | — | — | US | disclosed |