Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4838365 | 0.76 | THRB (0.38) | THRBLMNA | |
| SCHEMBL1578031 | 0.72 | THRB (0.40) | THRBLMNA | |
| SCHEMBL9678566 | 0.72 | LMNA (0.39) | THRBLMNA | |
| SCHEMBL9258805 | 0.72 | LMNA (0.39) | THRBLMNA | |
| SCHEMBL8685281 | 0.70 | THRB (0.38) | THRBLMNA | |
| SCHEMBL29156560 | 0.70 | THRB (0.38) | THRBLMNA | |
| SCHEMBL12272867 | 0.70 | THRB (0.33) | THRBLMNA | |
| SCHEMBL1086105 | 0.69 | — | — | |
| SCHEMBL12272470 | 0.69 | LMNA (0.36) | THRBLMNA | |
| SCHEMBL9310264 | 0.68 | THRB (0.36) | THRBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8153820-B2 | Method for the production of N-substituted (3-dihalomethyl-1-methylpyrazol-4-yl) carboxamides | BASF SE (DE) | 2012-04-10 | — | — | US | disclosed |
| US-20100174094-A1 | Method for the Production of N-Substituted (3-Dihalomethyl-1-Methyl-Pyrazole-4-yl) Carboxamides | BASF SE (DE) | 2010-07-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100174094-A1 | Method for the Production of N-Substituted (3-Dihalomethyl-1-Methyl-Pyrazole-4-yl) Carboxamides | CBR3, CBR1, CYC1 | THRB 3272/4885LMNA 505/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.