Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 4/20 | 0.44 |
| ▸ | CA2 | P00918 | 4/20 | 0.44 |
| ▸ | CA7 | P43166 | 3/20 | 0.44 |
| ▸ | CA9 | Q16790 | 3/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17529727 | 0.90 | ALOX5 (0.45) | SMN1; SMN2CA1CA2CA7CA9 | |
| SCHEMBL17529711 | 0.88 | ALOX5 (0.47) | SMN1; SMN2CA1CA2CA7CA9 | |
| SCHEMBL17529692 | 0.87 | PPARA (0.48) | SMN1; SMN2CA1CA2CA7CA9 | |
| SCHEMBL17529847 | 0.87 | PPARA (0.48) | SMN1; SMN2CA1CA2CA7CA9 | |
| SCHEMBL17529835 | 0.87 | PPARA (0.48) | SMN1; SMN2CA1CA2CA7CA9 | |
| SCHEMBL8677993 | 0.85 | CA1 (0.42) | SMN1; SMN2CA1CA2CA7CA9 | |
| SCHEMBL17529880 | 0.80 | CA1 (0.46) | SMN1; SMN2CA1CA2CA7CA9 | |
| SCHEMBL2332056 | 0.77 | CA1 (0.48) | SMN1; SMN2CA1CA2CA7CA9 | |
| SCHEMBL8208812 | 0.77 | ALDH1A1 (0.40) | SMN1; SMN2CA1CA2CA7CA9 | |
| SCHEMBL8780913 | 0.77 | CA1 (0.42) | SMN1; SMN2CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0788405-A1 | CATALYST FOR THE PREPARATION OF LINEAR CARBON MONOXIDE/ALPHA-OLEFIN COPOLYMERS | THE DOW CHEMICAL COMPANY (US) | 1997-08-13 | — | — | EP | claimed |
| WO-1996001690-A1 | CATALYST FOR THE PREPARATION OF LINEAR CARBON MONOXIDE/ALPHA-OLEFIN COPOLYMERS | THE DOW CHEMICAL COMPANY (US) | 1996-01-25 | — | — | WO | claimed |
| EP-0257663-B1 | CATALYST COMPOSITIONS, OLEFIN/CO COPOLYMERIZATION PROCESS AND BISPHOSPHINE COMPOUNDS | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1992-01-15 | — | — | EP | claimed |
| EP-0257663-A2 | Catalyst compositions, olefin/co copolymerization process and bisphosphine compounds | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1988-03-02 | — | — | EP | claimed |
| EP-2164831-B1 | METHOD FOR THE PRODUCTION OF N-SUBSTITUTED (3-DIHALOMETHYL-1-METHYL-PYRAZOLE-4-YL) CARBOXAMIDES | BASF SE (DE) | 2013-07-17 | — | — | EP | disclosed |
| US-8153820-B2 | Method for the production of N-substituted (3-dihalomethyl-1-methylpyrazol-4-yl) carboxamides | BASF SE (DE) | 2012-04-10 | — | — | US | disclosed |
| US-20100174094-A1 | Method for the Production of N-Substituted (3-Dihalomethyl-1-Methyl-Pyrazole-4-yl) Carboxamides | BASF SE (DE) | 2010-07-08 | — | — | US | disclosed |
| EP-1475394-A2 | Olefin polymerization process | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2004-11-10 | — | — | EP | disclosed |
| US-6103920-A | Olefin polymerization process | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2000-08-15 | — | — | US | disclosed |
| EP-0650761-B1 | Catalyst composition and process for the preparation of polymers | SHELL INT RESEARCH (NL) | 1999-01-13 | — | — | EP | disclosed |
| EP-0562698-B1 | Novel olefin/CO copolymers | SHELL INT RESEARCH (NL) | 1997-09-24 | — | — | EP | disclosed |
| EP-0788405-A1 | CATALYST FOR THE PREPARATION OF LINEAR CARBON MONOXIDE/ALPHA-OLEFIN COPOLYMERS | THE DOW CHEMICAL COMPANY (US) | 1997-08-13 | — | — | EP | disclosed |
| EP-0298540-A2 | Preparation of phosphides | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1989-01-11 | — | — | EP | disclosed |
| EP-0285218-A2 | Removal of catalyst remnants from olefin/CO copolymers | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1988-10-05 | — | — | EP | disclosed |
| EP-0283092-A1 | Process for removing palladium catalyst remnants from copolymers of carbon monoxide with one or more olefinically unsaturated compounds | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1988-09-21 | — | — | EP | disclosed |
| EP-0272728-A2 | Process for the preparation of polymers of C0 and olefinically unsaturated compounds | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1988-06-29 | — | — | EP | disclosed |
| EP-0272727-A2 | Novel polymers of carbon monoxide and alpha-olefinically unsaturated compounds | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1988-06-29 | — | — | EP | disclosed |
| EP-0269154-A2 | Novel olefin/CO copolymers | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1988-06-01 | — | — | EP | disclosed |
| EP-0263564-A1 | Catalyst compositions and olefin/CO-copolymerization process | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1988-04-13 | — | — | EP | disclosed |
| EP-0257663-A2 | Catalyst compositions, olefin/co copolymerization process and bisphosphine compounds | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1988-03-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100174094-A1 | Method for the Production of N-Substituted (3-Dihalomethyl-1-Methyl-Pyrazole-4-yl) Carboxamides | CBR3, CBR1, CYC1 | SMN1; SMN2 3019/4885CA1 667/4885CA2 698/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.