SCHEMBL1086248

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1086375	0.90	RIPK1 (0.53)	RIPK1CYP2D6ALDH1A1CYP3A4USP2
	SCHEMBL1086769	0.88	CYP2D6 (0.64)	RIPK1CYP2D6ALDH1A1CYP3A4USP2
	SCHEMBL1086392	0.88	RIPK1 (0.53)	RIPK1CYP2D6ALDH1A1CYP3A4TSHR
	SCHEMBL1086305	0.85	CYP2D6 (0.51)	CYP2D6ALDH1A1CYP3A4USP2CYP1A2
	SCHEMBL1086246	0.85	RIPK1 (0.49)	RIPK1CYP2D6ALDH1A1CYP3A4CYP1A2
	SCHEMBL1085767	0.83	RIPK1 (0.52)	RIPK1CYP2D6ALDH1A1CYP3A4CYP1A2
	SCHEMBL1085734	0.83	RIPK1 (0.48)	RIPK1CYP2D6ALDH1A1CYP3A4CYP1A2
	SCHEMBL1086067	0.83	MEN1 (0.59)	CYP2D6ALDH1A1CYP3A4USP2CYP1A2
	SCHEMBL4258714	0.82	RIPK1 (0.48)	RIPK1CYP2D6ALDH1A1CYP3A4CYP1A2
	SCHEMBL1086418	0.82	RIPK1 (0.48)	RIPK1CYP2D6ALDH1A1CYP3A4CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.