SCHEMBL4258714

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1085767	0.90	RIPK1 (0.52)	RIPK1MEN1RAB9AKMT2AALDH1A1
	SCHEMBL1086418	0.89	RIPK1 (0.48)	RIPK1ALDH1A1CYP2D6CYP2C19KDM4E
	SCHEMBL1086419	0.86	RIPK1 (0.48)	RIPK1ALDH1A1CYP2D6CYP2C19KDM4E
	SCHEMBL1085734	0.83	RIPK1 (0.48)	RIPK1MEN1KMT2AALDH1A1CYP2D6
	SCHEMBL1086096	0.83	RIPK1 (0.44)	RIPK1ALDH1A1CYP2D6CYP2C19KDM4E
	SCHEMBL1086117	0.83	RIPK1 (0.42)	RIPK1MEN1KMT2AALDH1A1CYP2D6
	SCHEMBL1086967	0.83	RIPK1 (0.46)	RIPK1MEN1KMT2AALDH1A1CYP2D6
	SCHEMBL1086248	0.82	RIPK1 (0.55)	RIPK1MEN1KMT2AALDH1A1CYP2D6
	SCHEMBL1086206	0.82	RIPK1 (0.48)	RIPK1ALDH1A1CYP2D6CYP2C19KDM4E
	SCHEMBL1086693	0.81	GRM5 (0.47)	RIPK1ALDH1A1TACR2TACR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.