Fluoride

Fluoride

SCHEMBL1086263

CCCCN(CCCC)CCCC.F.F.F

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.43
CA1 P00915 2/20 0.43
CA9 Q16790 2/20 0.43
TSHR P16473 2/20 0.43
LMNA P02545 1/20 0.43
MAPT P10636 1/20 0.41
DNM1 Q05193 3/20 0.40
KDM5A P29375 3/20 0.40
THRB P10828 1/20 0.40
PHF8 Q9UPP1 2/20 0.38
ALDH1A1 P00352 1/20 0.38
ALDH2 P05091 1/20 0.38
KDM4C Q9H3R0 1/20 0.38
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluoride SCHEMBL63194 1.00 CA12 (0.43) CA12CA1CA9TSHRLMNA
Fluoride SCHEMBL3200626 0.96 CA12 (0.42) CA12CA1CA9TSHRLMNA
SCHEMBL27566038 0.96 TSHR (0.46) CA12CA1CA9TSHRLMNA
SCHEMBL896 0.96 TSHR (0.46) CA12CA1CA9TSHRLMNA
SCHEMBL3904839 0.96 TSHR (0.46) CA12CA1CA9TSHRLMNA
Fluoride SCHEMBL7561486 0.93 CA12 (0.40) CA12CA1CA9TSHRLMNA
Iodide SCHEMBL328995 0.92 CA12 (0.43) CA12CA1CA9TSHRLMNA
Hydrochloric Acid SCHEMBL180393 0.92 DNM1 (0.45) CA12CA1CA9TSHRLMNA
Water SCHEMBL8722192 0.92 CA12 (0.43) CA12CA1CA9TSHRLMNA
SCHEMBL1897739 0.92 CA12 (0.43) CA12CA1CA9TSHRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7994207-B2 Process for preparing fluoromethyl-substituted heterocyclic compounds BASF SE (DE) 2011-08-09 US claimed
US-20100022782-A1 Process for Preparing Fluoromethyl-Substituted Heterocyclic Compounds BASF SE (DE) 2010-01-28 US claimed
EP-2121618-A1 PROCESS FOR PREPARING FLUOROMETHYL-SUBSTITUTED HETEROCYCLIC COMPOUNDS BASF SE (DE) 2009-11-25 EP claimed
WO-2008077907-A1 PROCESS FOR PREPARING FLUOROMETHYL-SUBSTITUTED HETEROCYCLIC COMPOUNDS BASF SE (DE) 2008-07-03 WO claimed
US-12276037-B2 Anodized titanium material and method for producing the same YAMAGUCHI PREFECTURAL INDUSTRIAL TECHNOLOGY INSTITUTE (JP) 2025-04-15 US disclosed
CN-112585302-B Anodic titanium oxide material and method for producing same 地方独立行政法人山口县产业技术研究院 2025-03-18 CN disclosed
US-20210207283-A1 ANODIZED TITANIUM MATERIAL AND METHOD FOR PRODUCING THE SAME YAMAGUCHI PREFECTURAL INDUSTRIAL TECHNOLOGY INSTITUTE (JP) 2021-07-08 US disclosed
CN-112585302-A Anodic titanium oxide material and method for producing same 地方独立行政法人山口县产业技术研究院 2021-03-30 CN disclosed
US-10100134-B2 Method for manufacturing polymer compound TOKYO OHKA KOGYO CO., LTD. (JP) 2018-10-16 US disclosed
EP-2742153-B1 PROTEIN AND PEPTIDE LIBRARIES MASSACHUSETTS GEN HOSPITAL (US) 2018-09-05 EP disclosed
US-20170198282-A1 PROTEIN AND PEPTIDE LIBRARIES THE GENERAL HOSPITAL CORPORATION (US) 2017-07-13 US disclosed
US-20170166664-A1 METHOD FOR MANUFACTURING POLYMER COMPOUND TOKYO OHKA KOGYO CO., LTD. (JP) 2017-06-15 US disclosed
EP-2121618-A1 PROCESS FOR PREPARING FLUOROMETHYL-SUBSTITUTED HETEROCYCLIC COMPOUNDS BASF SE (DE) 2009-11-25 EP disclosed
WO-2008145740-A1 METHOD FOR THE PRODUCTION OF N-SUBSTITUTED (3-DIHALOMETHYL-1-METHYL-PYRAZOLE-4-YL) CARBOXAMIDES BASF SE (DE) 2008-12-04 WO disclosed
WO-2008077907-A1 PROCESS FOR PREPARING FLUOROMETHYL-SUBSTITUTED HETEROCYCLIC COMPOUNDS BASF SE (DE) 2008-07-03 WO disclosed
US-6118033-A Method for preparing heptafluoropropane SOLVAY (SOCIETE ANONYME) (BE) 2000-09-12 US disclosed
EP-0021331-B1 PROCESS FOR PRODUCING SULFUR TETRAFLUORIDE HOECHST AKTIENGESELLSCHAFT (DE) 1982-05-26 EP disclosed
EP-0021331-A1 Process for producing sulfur tetrafluoride HOECHST AKTIENGESELLSCHAFT (DE) 1981-01-07 EP disclosed
EP-0005810-B1 METHOD FOR THE PREPARATION OF ORGANIC FLUORO COMPOUNDS HOECHST AKTIENGESELLSCHAFT (DE) 1980-11-12 EP disclosed
EP-0005810-A1 Method for the preparation of organic fluoro compounds HOECHST AKTIENGESELLSCHAFT (DE) 1979-12-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100022782-A1 Process for Preparing Fluoromethyl-Substituted Heterocyclic Compounds AFF4, AFF1, F12 CA12 807/4885CA1 769/4885CA9 439/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.