Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.40 |
| ▸ | KDM5A | P29375 | 3/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27566038 | 0.96 | TSHR (0.46) | CA12CA1CA9TSHRLMNA | |
| SCHEMBL896 | 0.96 | TSHR (0.46) | CA12CA1CA9TSHRLMNA | |
| SCHEMBL3904839 | 0.96 | TSHR (0.46) | CA12CA1CA9TSHRLMNA | |
| Iodide SCHEMBL1758272 | 0.93 | DNM1 (0.50) | CA12CA1CA9TSHRLMNA | |
| SCHEMBL1897739 | 0.92 | CA12 (0.43) | CA12CA1CA9TSHRLMNA | |
| SCHEMBL6664330 | 0.92 | CA12 (0.43) | CA12CA1CA9TSHRLMNA | |
| Ethane SCHEMBL4431820 | 0.92 | CA12 (0.43) | CA12CA1CA9TSHRLMNA | |
| Water SCHEMBL8722192 | 0.92 | CA12 (0.43) | CA12CA1CA9TSHRLMNA | |
| Bromide SCHEMBL466549 | 0.92 | DNM1 (0.45) | CA12CA1CA9TSHRLMNA | |
| Hydrochloric Acid SCHEMBL180393 | 0.92 | DNM1 (0.45) | CA12CA1CA9TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 186 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107602361-A | A kind of α, the preparation method of alpha-beta unsaturated acetyenic ketone compounds | 大连理工大学 | 2018-01-19 | — | — | CN | claimed |
| US-20150197668-A1 | POLYESTER PROCESSES | XEROX CORPORATION (US) | 2015-07-16 | — | — | US | claimed |
| CN-102347138-A | Electrolyte composition for dye-sensitized solar cell and solar cell using same | EVERLIGHT CHEMICAL IND CO LTD | 2012-02-08 | — | — | CN | claimed |
| US-20110100461-A1 | ELECTROLYTE COMPOSITION AND DYE-SENSITIZED SOLAR CELL HAVING THE SAME | EVERLIGHT USA, INC. (US) | 2011-05-05 | — | — | US | claimed |
| US-20110100464-A1 | Electrolyte composition and dye-sensitized solar cell using the same | EVERLIGHT USA, INC. (US) | 2011-05-05 | — | — | US | claimed |
| US-20070088147-A1 | Epoxy resin, epoxy resin composition including the epoxy resin and method of preparing the epoxy resin | DPI CO., LTD. (KR) | 2007-04-19 | — | — | US | claimed |
| US-20060241114-A1 | Derivatives of azasugars as anticancer agents | RANBAXY LABORATORIES LIMITED (IN) | 2006-10-26 | — | — | US | claimed |
| EP-1597231-A1 | DERIVATIVES OF AZASUGARS AS ANTICANCER AGENTS | RANBAXY LABORATORIES, LTD. (IN) | 2005-11-23 | — | — | EP | claimed |
| WO-2004074251-A1 | DERIVATIVES OF AZASUGARS AS ANTICANCER AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2004-09-02 | — | — | WO | claimed |
| US-6399808-B1 | REACTING AMINE WITH CARBON DIOXIDE IN ANHYDROUS SOLVENT | UNIVERSITY OF SOUTH FLORIDA | 2002-06-04 | — | — | US | claimed |
| US-6194471-B1 | WATER-FREE FLUID MINERAL ACID SALTS OF FATTY ACID AMINE DERIVATIVES (FAAD'S) FOR USE AS ANTISTRIPPING AGENTS IN HOT ASPHALTS; MIXTURE OF A FAAD'D WITH A MINERAL ACID (OR ITS AMINE SALT) IN THE PRESENCE OF A POLAR ORGANIC SOLVENT | JPMORGAN CHASE BANK, N.A. | 2001-02-27 | — | — | US | claimed |
| WO-2000050389-A1 | EFFICIENT CARBAMATE SYNTHESIS | UNIVERSITY OF SOUTH FLORIDA (US) | 2000-08-31 | — | — | WO | claimed |
| US-12077535-B2 | Derivatives of resiquimod | SUPERB WISDOM LIMITED (WS) | 2024-09-03 | — | — | US | disclosed |
| CN-115461507-B | Method for producing coagulated material | DIC株式会社 | 2024-03-19 | — | — | CN | disclosed |
| EP-3537140-B1 | USE OF A GAS DETECTING SENSOR | LG CHEMICAL LTD (KR) | 2023-12-27 | — | — | EP | disclosed |
| EP-3537138-B1 | QUANTUM DOT BIOSENSOR | LG CHEMICAL LTD (KR) | 2023-12-27 | — | — | EP | disclosed |
| US-4594291-A | Blend of epoxy resin and extender | THE DOW CHEMICAL COMPANY (US) | 1986-06-10 | — | — | US | disclosed |
| WO-1986002085-A1 | CURABLE COMPOSITIONS CONTAINING A POLYEPOXIDE AND A HALOGENATED DIHYDRIC PHENOL AND IMPREGNATED SUBSTRATES AND LAMINATES PREPARED THEREFROM | THE DOW CHEMICAL COMPANY (US) | 1986-04-10 | — | — | WO | disclosed |
| US-4554285-A | HORTICULTURE | BASF AKTIENGESELLSCHAFT (DE) | 1985-11-19 | — | — | US | disclosed |
| EP-0126225-A1 | Process for the preparation of substituted trialkylsilyloxymalonic-acid dinitriles | BAYER AG (DE) | 1984-11-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060241114-A1 | Derivatives of azasugars as anticancer agents | NTPCR, DUT, AZI2 | CA12 1400/4885CA1 3361/4885CA9 744/4885 |
| US-12077535-B2 | Derivatives of resiquimod | MYD88, TLR7, HLA-DRB1 | CA12 516/4885CA1 1098/4885CA9 698/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.