SCHEMBL1086282

SCHEMBL1086282

CCOc1ccc(C(N)=O)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP10 Q53GL7 9/20 1.00
PRSS1 P07477 1/20 0.66
PRSS2 P07478 1/20 0.66
PRSS3 P35030 1/20 0.66
NPC1 O15118 1/20 0.61
PLK1 P53350 1/20 0.61
PARP4 Q9UKK3 2/20 0.61
PARP2 Q9UGN5 2/20 0.61
CA1 P00915 1/20 0.61
CA2 P00918 1/20 0.61
PARP1 P09874 1/20 0.61
POLB P06746 1/20 0.60
ALDH1A1 P00352 3/20 0.59
KMT2A Q03164 2/20 0.59
PARP15 Q460N3 2/20 0.59
PARP14 Q460N5 1/20 0.59
PARP16 Q8N5Y8 1/20 0.59
PARP11 Q9NR21 1/20 0.59
NQO1 P15559 1/20 0.58
PLA2G4B P0C869 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29960960 1.00 PARP10 (1.00) PARP10PRSS1PRSS2PRSS3NPC1
Hydrochloric Acid SCHEMBL4381217 0.98 PARP10 (0.96) PARP10PRSS1PRSS2PRSS3NPC1
Hydrochloric Acid SCHEMBL5494037 0.98 PARP10 (0.96) PARP10PRSS1PRSS2PRSS3NPC1
Benzamide SCHEMBL5531824 0.93 PARP10 (0.86) PARP10PRSS1PRSS2PRSS3NPC1
SCHEMBL606438 0.84 PARP10 (0.72) PARP10PLK1PARP4PARP2CA1
SCHEMBL1086686 0.84 PARP10 (0.72) PARP10NPC1PLA2G4B
SCHEMBL3017507 0.83 PARP10 (0.71) PARP10PRSS1PARP4PARP2CA1
SCHEMBL7439846 0.83 PARP10 (0.71) PARP10PRSS1PRSS2PRSS3NPC1
SCHEMBL1367365 0.83 PARP10 (0.70) PARP10PRSS1PRSS2PRSS3NPC1
SCHEMBL845348 0.83 NPSR1 (0.79) PARP10PRSS1PRSS2PRSS3NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 371 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12575248-B2 Zinc oxide nanomaterial and preparation method thereof and semiconductor device TCL TECHNOLOGY GROUP CORPORATION (CN) 2026-03-10 US claimed
EP-4167307-B1 ZINC OXIDE NANOMATERIAL AND PREPARATION METHOD THEREFOR, AND SEMICONDUCTOR DEVICE TCL TECH GROUP CORP (CN) 2025-02-05 EP claimed
CN-116375549-A Method and system for synthesizing amide compound from nitrile compound 深圳湾实验室 2023-07-04 CN claimed
EP-4167307-A1 ZINC OXIDE NANOMATERIAL AND PREPARATION METHOD THEREFOR, AND SEMICONDUCTOR DEVICE TCL Technology Group Corporation (CN) 2023-04-19 EP claimed
CN-113809245-B Zinc oxide nano material, preparation method thereof and semiconductor device TCL科技集团股份有限公司 2022-11-04 CN claimed
US-20220336764-A1 ZINC OXIDE NANOMATERIAL AND PREPARATION METHOD THEREOF AND SEMICONDUCTOR DEVICE U.S. DEPARTMENT OF ENERGY 2022-10-20 US claimed
CN-113809245-A Zinc oxide nano material, preparation method thereof and semiconductor device TCL科技集团股份有限公司 2021-12-17 CN claimed
EP-1773768-B1 PYRROLE DERIVATIVES AS PHARMACEUTICAL AGENTS EXELIXIS INC (US) 2018-08-22 EP claimed
US-8153795-B2 Substituted 1-oxa-3,8-diazaspiro[4.5]-decan-2-one-compounds and the use thereof for producing drugs GRUENENTHAL GMBH (DE) 2012-04-10 US claimed
EP-1506196-B1 PYRAZOLOPYRIMIDINES AS SODIUM CHANNEL INHIBITORS ICAGEN INC (US) 2012-01-18 EP claimed
US-6262272-B1 REACTING FURAN CARBOXYLIC ACID DERIVATIVE WITH ACID CHLORIDE OR ACID ANHYDRIDE IN INERT SOLVENT CONTAINING ACID RECEPTOR; ADDING AROMATIC AMINE COMPOUND TO FORM PYRROLE CARBOXAMIDE COMPOUND PFIZER INC 2001-07-17 US claimed
EP-1104404-A1 SUBSTITUTED ISOQUINOLINE DERIVATIVES AND THEIR USE AS ANTICONVULSANTS SMITHKLINE BEECHAM PLC (GB) 2001-06-06 EP claimed
EP-1102769-A2 TRICYCLIC CARBOXAMIDES SMITHKLINE BEECHAM PLC (GB) 2001-05-30 EP claimed
EP-1030838-A1 METHOD OF SYNTHESIS OF PYRROLE AMIDES Pfizer Products Inc. (US) 2000-08-30 EP claimed
WO-2000047578-A1 HETEROARYL AMIDINES, METHYLAMIDINES AND GUANIDINES AS PROTEASE INHIBITORS 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) 2000-08-17 WO claimed
WO-2000045635-A1 THIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF LION BIOSCIENCE AG (DE) 2000-08-10 WO claimed
WO-2000025768-A1 OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF TREGA BIOSCIENCES, INC. (US) 2000-05-11 WO claimed
WO-2000009486-A1 SUBSTITUTED ISOQUINOLINE DERIVATIVES AND THEIR USE AS ANTICONVULSIVANTS SMITHKLINE BEECHAM P.L.C. (GB) 2000-02-24 WO claimed
WO-2000008020-A2 TRICYCLIC CARBOXAMIDES SMITHKLINE BEECHAM P.L.C. (GB) 2000-02-17 WO claimed
WO-1999025684-A1 METHOD OF SYNTHESIS OF PYRROLE AMIDES PFIZER PRODUCTS INC. (US) 1999-05-27 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12575248-B2 Zinc oxide nanomaterial and preparation method thereof and semiconductor device ZRANB2, ZKSCAN2, SLC39A3 PARP10 2721/4885PRSS1 4453/4885PRSS2 4287/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.