Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.79 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.70 |
| ▸ | NPC1 | O15118 | 3/20 | 0.66 |
| ▸ | PLK1 | P53350 | 1/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.65 |
| ▸ | HPGD | P15428 | 5/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | RAB9A | P51151 | 2/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.64 |
| ▸ | RECQL | P46063 | 1/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | NQO1 | P15559 | 1/20 | 0.64 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.61 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11576081 | 0.92 | KMT2A (0.69) | NPSR1KMT2APARP10NPC1PLK1 | |
| SCHEMBL845256 | 0.92 | L3MBTL1 (0.77) | NPSR1KMT2APARP10NPC1PLK1 | |
| SCHEMBL30776959 | 0.92 | KMT2A (0.69) | NPSR1KMT2APARP10NPC1PLK1 | |
| SCHEMBL11042318 | 0.90 | KMT2A (0.67) | NPSR1KMT2APARP10NPC1PLK1 | |
| SCHEMBL20496443 | 0.90 | NPSR1 (0.67) | NPSR1KMT2APARP10NPC1PLK1 | |
| SCHEMBL6655854 | 0.90 | TSHR (0.70) | NPSR1KMT2APARP10NPC1PLK1 | |
| SCHEMBL11578668 | 0.90 | KMT2A (0.67) | NPSR1KMT2APARP10NPC1PLK1 | |
| SCHEMBL9549100 | 0.89 | KMT2A (0.65) | NPSR1KMT2APARP10NPC1PLK1 | |
| SCHEMBL16600543 | 0.89 | NPSR1 (0.65) | NPSR1KMT2APARP10NPC1PLK1 | |
| SCHEMBL11489003 | 0.87 | ALDH1A1 (0.66) | NPSR1KMT2APARP10NPC1PLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 127 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116354799-A | Preparation method of dapagliflozin intermediate | 江苏阿尔法药业股份有限公司 | 2023-06-30 | — | — | CN | claimed |
| CN-217248929-U | (5-bromo-2-chlorophenyl) (4-ethoxyphenyl) ketone preparation facilities | 河南科来福化工有限公司 | 2022-08-23 | — | — | CN | claimed |
| CN-108752184-B | Preparation method of SGLT2 inhibitor intermediate | 杭州科耀医药科技有限公司 | 2021-11-16 | — | — | CN | claimed |
| CN-112920030-A | Method for preparing dapagliflozin intermediate by one-pot method | 安庆奇创药业有限公司 | 2021-06-08 | — | — | CN | claimed |
| CN-109456268-A | The preparation of 3, the 4- dihydro-isoquinoline Alkaloid of C1 substitutions and its medical usage | 中国药科大学 | 2019-03-12 | — | — | CN | claimed |
| CN-104844573-A | Miazines BTK inhibitor, preparation method and medical application thereof | UNIV CHINA PHARMA | 2015-08-19 | — | — | CN | claimed |
| EP-0606198-A4 | MICROPOROUS HOLLOW FIBER OR FILM MEMBRANE OF POLY(PHENYLENE SULFIDE) (PPS). | DOW CHEMICAL CO (US) | 1995-01-25 | — | — | EP | claimed |
| EP-0606198-A1 | MICROPOROUS HOLLOW FIBER OR FILM MEMBRANE OF POLY(PHENYLENE SULFIDE) (PPS) | THE DOW CHEMICAL COMPANY (US) | 1994-07-20 | — | — | EP | claimed |
| WO-1993004223-A1 | MICROPOROUS HOLLOW FIBER OR FILM MEMBRANE OF POLY(PHENYLENE SULFIDE) (PPS) | THE DOW CHEMICAL COMPANY (US) | 1993-03-04 | — | — | WO | claimed |
| CN-118084636-A | Fully alkylated crown [4] arene and synthetic method and application thereof | 东北大学 | 2024-05-28 | — | — | CN | disclosed |
| CN-219409913-U | High-efficient pickling device | 河南科来福化工有限公司 | 2023-07-25 | — | — | CN | disclosed |
| CN-116354799-A | Preparation method of dapagliflozin intermediate | 江苏阿尔法药业股份有限公司 | 2023-06-30 | — | — | CN | disclosed |
| CN-116262691-A | (5-bromo-2-chlorophenyl) (4-fluorophenyl) methanone | 苏州小栗医药科技有限公司 | 2023-06-16 | — | — | CN | disclosed |
| CN-115536500-A | Preparation method of 2, 2-diaryl vinyl alkyl ether | 长沙资材科技有限公司 | 2022-12-30 | — | — | CN | disclosed |
| CN-88101892-A | insecticidal cyclopropyl-substituted di (aryl) compounds | — | 1988-11-02 | — | — | CN | disclosed |
| EP-0281891-A2 | Dye builders, their preparation and use | BAYER AG (DE) | 1988-09-14 | — | — | EP | disclosed |
| US-4550142-A | UNSATURATED RUBBER MODIFIED WITH AMINOBENZOPHENONE | NIPPON ZEON CO. LTD. (JP) | 1985-10-29 | — | — | US | disclosed |
| US-4115413-A | ACID FREE | BAYER AKTIENGESELLSCHAFT (DE) | 1978-09-19 | — | — | US | disclosed |
| US-4042603-A | SUBSTITUTED DIBENZOFURAN OR 9-FLUORENONE FROM A DIPHENYL ETHER OR BENZOPHENONE | UBE INDUSTRIES, LTD. (JA) | 1977-08-16 | — | — | US | disclosed |
| US-4042587-A | PESTICIDES | BASF AKTIENGESELLSCHAFT (DT) | 1977-08-16 | — | — | US | disclosed |