Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MC4R | P32245 | 1/20 | 0.33 |
| ▸ | MC5R | P33032 | 1/20 | 0.33 |
| ▸ | OXTR | P30559 | 1/20 | 0.33 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | STK17A | Q9UEE5 | 4/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | LOX | P28300 | 1/20 | 0.31 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.31 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | STK17B | O94768 | 1/20 | 0.30 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10483870 | 0.93 | CHRM2 (0.38) | CHRM2HTTMC4RMC5RCYP1A2 | |
| SCHEMBL10484102 | 0.83 | PDCD1 (0.38) | SIGMAR1CHRM2MC4RMC5ROXTR | |
| SCHEMBL22513143 | 0.83 | KDM4E (0.41) | CHRM2HTTCYP1A2CYP2D6POLB | |
| SCHEMBL7995516 | 0.83 | CHRM2 (0.38) | CHRM2HTTOXTRAVPR1APOLB | |
| SCHEMBL10862494 | 0.83 | SIGMAR1 (0.35) | SIGMAR1CHRM2HTTMC4RMC5R | |
| SCHEMBL10483918 | 0.78 | STK17A (0.36) | CHRM2MC4RMC5RCYP1A2CYP2D6 | |
| SCHEMBL11229247 | 0.76 | SIGMAR1 (0.46) | SIGMAR1CHRM2HTTMC4RMC5R | |
| SCHEMBL7992424 | 0.75 | SIRT6 (0.36) | SIGMAR1CHRM2MC4RMC5RMAOB | |
| SCHEMBL23066496 | 0.74 | SLC6A4 (0.44) | CYP2D6 | |
| SCHEMBL30570470 | 0.74 | SLC6A4 (0.44) | CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0192060-A1 | Heterocyclic compounds | NIHON BAYER AGROCHEM K.K. (JP) | 1986-08-27 | — | — | EP | disclosed |