Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KDM4A | O75164 | 1/20 | 0.43 |
| ▸ | TDP2 | O95551 | 1/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.43 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10373336 | 1.00 | ALDH1A1 (0.50) | ALDH1A1MAPK1HTTTDP1L3MBTL1 | |
| SCHEMBL11797633 | 0.99 | ALDH1A1 (0.49) | ALDH1A1MAPK1HTTTDP1L3MBTL1 | |
| Potassium Ion SCHEMBL11797628 | 0.89 | ALDH1A1 (0.48) | ALDH1A1MAPK1HTTTDP1L3MBTL1 | |
| SCHEMBL10813723 | 0.85 | ALDH1A1 (0.48) | ALDH1A1MAPK1HTTTDP1L3MBTL1 | |
| SCHEMBL10795482 | 0.82 | ALDH1A1 (0.45) | ALDH1A1MAPK1HTTTDP1L3MBTL1 | |
| SCHEMBL10811508 | 0.78 | ALDH1A1 (0.40) | ALDH1A1MAPK1HTTTDP1L3MBTL1 | |
| Potassium SCHEMBL11797636 | 0.73 | CYP1A2 (0.40) | ALDH1A1MAPK1HTTTDP1L3MBTL1 | |
| SCHEMBL2705062 | 0.72 | APEX1 (0.63) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL27447186 | 0.72 | CYP1A2 (0.43) | ALDH1A1TDP1L3MBTL1MEN1KMT2A | |
| SCHEMBL27446992 | 0.71 | CTSD (0.43) | ALDH1A1TDP1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0168112-A2 | Alpha-L-aspartyl-D-phenylglycine esters and amides useful as high intensity sweeteners | THE PROCTER & GAMBLE COMPANY (US) | 1986-01-15 | — | — | EP | disclosed |