Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | CASR | P41180 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18575578 | 0.78 | HTR1A (0.50) | CYP3A4CHRM2HTR1AADRA2AADORA3 | |
| SCHEMBL1132349 | 0.73 | CYP3A4 (0.66) | CYP3A4CHRM2HTR1AADRA2AADORA3 | |
| SCHEMBL4706959 | 0.73 | CYP3A4 (0.66) | CYP3A4CHRM2HTR1AADRA2AADORA3 | |
| SCHEMBL3927833 | 0.73 | CYP3A4 (0.66) | CYP3A4CHRM2HTR1AADRA2AADORA3 | |
| SCHEMBL18575438 | 0.72 | SMN1; SMN2 (0.47) | CYP3A4CHRM2HTR1AADRA2AADORA3 | |
| SCHEMBL18575542 | 0.72 | CASR (0.48) | CYP3A4CHRM2HTR1AADRA2AADORA3 | |
| SCHEMBL10863834 | 0.71 | CYP3A4 (0.33) | CYP3A4CHRM2HTR1AADRA2AADORA3 | |
| SCHEMBL10730601 | 0.70 | GAA (0.46) | CYP3A4CHRM2HTR1AADRA2AADORA3 | |
| SCHEMBL335144 | 0.70 | ESR1 (0.45) | CYP3A4CHRM2HTR1AADRA2AADORA3 | |
| SCHEMBL335282 | 0.70 | CYP3A4 (0.36) | CYP3A4CHRM2HTR1AADRA2AADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0192060-A1 | Heterocyclic compounds | NIHON BAYER AGROCHEM K.K. (JP) | 1986-08-27 | — | — | EP | disclosed |