Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.45 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.45 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.44 |
| ▸ | HTR3A | P46098 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.44 |
| ▸ | GALR3 | O60755 | 1/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18575578 | 0.90 | HTR1A (0.50) | LMNASLC6A2OPRM1SLC6A4CYP2D6 | |
| SCHEMBL18575438 | 0.82 | SMN1; SMN2 (0.47) | TAAR1LMNASLC6A2OPRM1SLC6A4 | |
| SCHEMBL13137649 | 0.82 | ESR1 (0.47) | ESR1ESR2PDCD1CD274HIF1A | |
| SCHEMBL1132349 | 0.80 | CYP3A4 (0.66) | TAAR1LMNASLC6A2OPRM1SLC6A4 | |
| SCHEMBL4706959 | 0.80 | CYP3A4 (0.66) | TAAR1LMNASLC6A2OPRM1SLC6A4 | |
| SCHEMBL3927833 | 0.80 | CYP3A4 (0.66) | TAAR1LMNASLC6A2OPRM1SLC6A4 | |
| SCHEMBL335330 | 0.79 | OPRK1 (0.50) | HIF1ATAAR1TSHRNFKB1LMNA | |
| SCHEMBL334407 | 0.79 | OPRK1 (0.50) | HIF1ATAAR1TSHRNFKB1LMNA | |
| SCHEMBL334522 | 0.78 | KMT2A (0.41) | TSHRLMNASLC6A2OPRM1SLC6A4 | |
| SCHEMBL18575437 | 0.78 | PKM (0.57) | TAAR1LMNAOPRM1SLC6A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110387035-B | Demulsifier, preparation method thereof and application thereof in demulsification of thick oil containing asphaltene | 中国石油化工股份有限公司 | 2022-01-04 | — | — | CN | disclosed |
| US-8097708-B2 | 10a-Azalide compound | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2012-01-17 | — | — | US | disclosed |
| US-20090281292-A1 | 10a-Azalide Compound | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2009-11-12 | — | — | US | disclosed |
| EP-1985620-A1 | 10a-AZALIDE COMPOUND | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2008-10-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090281292-A1 | 10a-Azalide Compound | IL17A, AZI2, HDAC9 | ESR1 4268/4885ESR2 4443/4885PDCD1 2475/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.