Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | MOK | Q9UQ07 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10865983 | 0.89 | NPC1 (0.55) | KMT2ANPC1RAB9ASMN1; SMN2TSHR | |
| SCHEMBL10864867 | 0.89 | L3MBTL1 (0.55) | KMT2ANPC1RAB9ASMN1; SMN2TSHR | |
| SCHEMBL10866084 | 0.89 | TSHR (0.54) | KMT2ANPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL10864983 | 0.80 | KMT2A (0.52) | KMT2ANPC1RAB9ASMN1; SMN2TSHR | |
| SCHEMBL10865350 | 0.80 | KDM4E (0.59) | KMT2ANPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL10864689 | 0.80 | HTR1A (0.53) | KMT2ANPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL11000678 | 0.80 | KDM4E (0.55) | KMT2ASMN1; SMN2MEN1TSHRKDM4E | |
| SCHEMBL10866115 | 0.79 | KMT2A (0.58) | KMT2ANPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL10998533 | 0.79 | KMT2A (0.53) | KMT2ANPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL10865581 | 0.79 | SCN9A (0.57) | KMT2ANPC1RAB9ASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0168812-A1 | 4-Amino-2-phenyl quinolines, methods and intermediates for their preparation and medicaments containing them | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1986-01-22 | — | — | EP | disclosed |
| US-4560692-A | ANTICONVULSANTS OR ANXIOLYTIC AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1985-12-24 | — | — | US | disclosed |