⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8556207 | 0.71 | MEN1 (0.33) | — | |
| SCHEMBL2270915 | 0.64 | — | — | |
| SCHEMBL2273263 | 0.64 | — | — | |
| SCHEMBL23948971 | 0.58 | — | — | |
| SCHEMBL173532 | 0.58 | — | — | |
| SCHEMBL174363 | 0.58 | — | — | |
| SCHEMBL2266002 | 0.58 | — | — | |
| SCHEMBL2265848 | 0.58 | NOX4 (0.43) | — | |
| SCHEMBL7700737 | 0.57 | PDE3B (0.39) | — | |
| SCHEMBL15408051 | 0.57 | PDE3B (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0185346-A2 | Imidazo derivatives, their preparation and medicaments containing these compounds | Dr. Karl Thomae GmbH (DE) | 1986-06-25 | — | — | EP | claimed |
| EP-0185346-A2 | Imidazo derivatives, their preparation and medicaments containing these compounds | Dr. Karl Thomae GmbH (DE) | 1986-06-25 | — | — | EP | disclosed |