⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL174363 | 1.00 | — | — | |
| SCHEMBL10675385 | 0.81 | — | — | |
| SCHEMBL10675382 | 0.80 | — | — | |
| SCHEMBL15966900 | 0.70 | PDE3B (0.35) | — | |
| SCHEMBL8556207 | 0.67 | MEN1 (0.33) | — | |
| SCHEMBL1245654 | 0.67 | LOXL2 (0.35) | — | |
| SCHEMBL545036 | 0.62 | LOXL2 (0.46) | — | |
| SCHEMBL199195 | 0.62 | — | — | |
| SCHEMBL557383 | 0.61 | MAP2K1 (0.44) | — | |
| SCHEMBL2273263 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1221 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250243203-A1 | NICOTINAMIDE- AND BENZAMIDE-BASED COMPOUNDS, CONJUGATES, AND COMPOSITIONS AS INHIBITORS OF TRANSLATIONAL- AND TRANSCRIPTIONAL-RELATED KINASES | PURDUE RESEARCH FOUNDATION | 2025-07-31 | — | — | US | claimed |
| CN-119522227-A | Macrocyclic compounds, pharmaceutical compositions and uses thereof | 贝达药业股份有限公司 | 2025-02-25 | — | — | CN | claimed |
| CN-119451675-A | Nicotinamide and benzamide based compounds, conjugates and compositions as inhibitors of translation and transcription related kinases | 普渡研究基金会 | 2025-02-14 | — | — | CN | claimed |
| EP-4504174-A2 | NICOTINAMIDE- AND BENZAMIDE-BASED COMPOUNDS, CONJUGATES, AND COMPOSITIONS AS INHIBITORS OF TRANSLATIONAL- AND TRANSCRIPTIONAL-RELATED KINASES | Purdue Research Foundation (US) | 2025-02-12 | — | — | EP | claimed |
| WO-2024017358-A1 | MACROCYCLIC COMPOUND, PHARMACEUTICAL COMPOSITION THEREOF, AND USE THEREOF | 贝达药业股份有限公司 | 2024-01-25 | — | — | WO | claimed |
| WO-2023196930-A2 | NICOTINAMIDE- AND BENZAMIDE-BASED COMPOUNDS, CONJUGATES, AND COMPOSITIONS AS INHIBITORS OF TRANSLATIONAL- AND TRANSCRIPTIONAL-RELATED KINASES | PURDUE RESEARCH FOUNDATION (US) | 2023-10-12 | — | — | WO | claimed |
| US-11547701-B2 | Compounds and compositions for the inhibition of NAMPT | VALO HEALTH, INC. (US) | 2023-01-10 | — | — | US | claimed |
| US-20210244717-A1 | NOVEL COMPOUNDS AND COMPOSITIONS FOR THE INHIBITION OF NAMPT | Valo Health, LLC | 2021-08-12 | — | — | US | claimed |
| US-10772874-B2 | Compounds and compositions for the inhibition of NAMPT | VALO HEALTH, INC. | 2020-09-15 | — | — | US | claimed |
| US-10456382-B2 | Compounds and compositions for the inhibition of NAMPT | FORMA TM, LLC (US) | 2019-10-29 | — | — | US | claimed |
| US-4769313-A | Image forming method utilizing accelerated desilverization of color photographic material containing magneta coupler | FUJI PHOTO FILM CO., LTD. (JP) | 1988-09-06 | — | — | US | claimed |
| US-4735893-A | PYRAZOLO-AZOLE MAGNETA COUPLER, IMAGE STABILIZER | FUJI PHOTO FILM CO., LTD. (JP) | 1988-04-05 | — | — | US | claimed |
| US-4728598-A | IMIDAZO(1,2-B)PYRAZOLE NUCLEUS | EASTMAN KODAK COMPANY (US) | 1988-03-01 | — | — | US | claimed |
| EP-0248442-A2 | Silver halide photographic material | FUJI PHOTO FILM CO., LTD. (JP) | 1987-12-09 | — | — | EP | claimed |
| EP-0203935-A1 | PHOTOGRAPHIC COLOR COUPLERS, PHOTOGRAPHIC MATERIALS CONTAINING THEM AND METHOD OF FORMING DYE IMAGES. | KODAK LTD (GB) | 1986-12-10 | — | — | EP | claimed |
| US-H122-H | PYRAZOLOAZOLE-TYPE MAGENTA COUPLER DISPERSED IN A HIGH-BOILING PHOSPHATE SOLVENT | FUJI PHOTO FILM CO., LTD. (JP) | 1986-09-02 | — | — | US | claimed |
| US-4607003-A | Photographic element | FUJI PHOTO FILM CO., LTD. (JP) | 1986-08-19 | — | — | US | claimed |
| WO-1986002467-A1 | PHOTOGRAPHIC COLOR COUPLERS, PHOTOGRAPHIC MATERIALS CONTAINING THEM AND METHOD OF FORMING DYE IMAGES | KODAK LIMITED (GB) | 1986-04-24 | — | — | WO | claimed |
| EP-0170164-A2 | Silver halide color photographic light-sensitive material | FUJI PHOTO FILM CO., LTD. (JP) | 1986-02-05 | — | — | EP | claimed |
| EP-0164130-A2 | Silver halide color photographic light-sensitive material | FUJI PHOTO FILM CO., LTD. (JP) | 1985-12-11 | — | — | EP | claimed |