Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.50 |
| ▸ | GRM5 | P41594 | 7/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | THPO | P40225 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6274089 | 0.94 | GRM5 (0.42) | APPGRM5KCNH2 | |
| SCHEMBL4737005 | 0.82 | GRM5 (0.49) | GRM5NPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL9390799 | 0.82 | ACHE (0.36) | GRM5KCNH2 | |
| SCHEMBL7638010 | 0.82 | ACHE (0.36) | GRM5NPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL456129 | 0.80 | APP (0.57) | APPGRM5NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL12344492 | 0.77 | CLK4 (0.46) | GRM5 | |
| SCHEMBL7632264 | 0.77 | ACHE (0.42) | CYP3A4 | |
| SCHEMBL4734252 | 0.77 | CA12 (0.41) | ALDH1A1LMNACA12CA1CA2 | |
| SCHEMBL6364777 | 0.77 | APP (0.75) | APPGRM5NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL23867871 | 0.75 | APP (0.50) | APPGRM5NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8153726-B2 | Highly oxygen permeable rigid contact lenses from polyacetylenes | THE LAGADO CORPORATION (US) | 2012-04-10 | — | — | US | disclosed |
| WO-2007041166-A2 | HIGHLY OXYGEN PERMEABLE RIGID CONTACT LENSES FROM POLYACETYLENES | THE LAGADO CORPORATION (US) | 2007-04-12 | — | — | WO | disclosed |
| US-20070078245-A1 | Highly Oxygen Permeable Rigid Contact Lenses from Polyacetylenes | THE LAGADO CORPORATION (US) | 2007-04-05 | — | — | US | disclosed |