Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 5/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1086629 | 0.94 | APP (0.50) | GRM5APPKCNH2 | |
| SCHEMBL4737005 | 0.88 | GRM5 (0.49) | GRM5ACHE | |
| SCHEMBL9390799 | 0.87 | ACHE (0.36) | GRM5ACHEKCNH2 | |
| SCHEMBL7638010 | 0.87 | ACHE (0.36) | GRM5ACHE | |
| SCHEMBL12344492 | 0.82 | CLK4 (0.46) | GRM5 | |
| SCHEMBL4734252 | 0.82 | CA12 (0.41) | ACHE | |
| SCHEMBL7632264 | 0.82 | ACHE (0.42) | ACHE | |
| SCHEMBL4572715 | 0.79 | ACHE (0.48) | ACHE | |
| SCHEMBL4735342 | 0.74 | GRM5 (0.48) | GRM5APP | |
| SCHEMBL456129 | 0.71 | APP (0.57) | GRM5APPKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1113017-B1 | SILOLE DERIVATIVES AND ORGANIC ELECTROLUMINESCENT ELEMENT CONTAINING THE SAME | CHISSO CORP (JP) | 2005-12-21 | — | — | EP | disclosed |
| US-6376694-B1 | Silole derivatives and organic electroluminescent element containing the same | CHISSO CORPORATION (JP) | 2002-04-23 | — | — | US | disclosed |
| EP-1113017-A1 | SILOLE DERIVATIVES AND ORGANIC ELECTROLUMINESCENT ELEMENT CONTAINING THE SAME | CHISSO CORPORATION (JP) | 2001-07-04 | — | — | EP | disclosed |